| 低浓度铅对微循环的影响 |
| |
| 引用本文： | 阮素云,华燕,沈红,陈良,秦逸秋. 低浓度铅对微循环的影响[J]. 职业卫生与应急救援, 2001, 19(1): 3-5 |
| |
| 作者姓名： | 阮素云 华燕 沈红 陈良 秦逸秋 |
| |
| 作者单位： | 1. 上海市疾病预防控制中心环境与职业医学科, 上海 200336
2. 华东师范大学生物系, 上海 200062 |
| |
| 摘 要： | 目的 探讨低浓度铅影响血压和血红蛋白的可能机制及其影响循环的作用方式。方法 采用钙细胞化学定位及电子探针－X射线能量色散分析，观察大鼠饮用铅水30mg/L三个月后，血铅浓度与脑微循环中红细胞形态、结构及钙分布的关系。结果 铅染毒组，钙在微血管内、外二侧及红细胞质膜内侧聚积，同时电子探针能量色散谱分析显示：铅染毒组， 血管腔外钙反应颗粒中出现明显铅峰。结论 血铅浓度在100μg/L左右即可影响血液及循环系统，其作用方式与铅引起的钙分布异常有关。
|
| 关 键 词： | 低浓度铅 微循环 铅中毒 |
| 文章编号： | 1007-1326(2001)01-0003-03 |
| 修稿时间： | 2000-12-28 |
EFECTS OF LOW LEVEL LEADON MICROCIRCULATION |
| |
| RUAN Su-yun,HUA Yan,SHEN Hong,et al.. EFECTS OF LOW LEVEL LEADON MICROCIRCULATION[J]. Occupational Health and Emergency Rescue, 2001, 19(1): 3-5 |
| |
| Authors: | RUAN Su-yun HUA Yan SHEN Hong et al. |
| |
| Abstract: | Objective To explore toxic effects of low level lead on blood pressure and hemoglobin(Hb) as well as microcirculation. Methods Rats were fed with drinking water containing 30mg/L lead for three months. Calcium cytochemistry and electron probe-energy dispersive X-ray(EDX) analysis was used to observe the relations between blood lead levels and calcium distribution in red blood cells and microcirculation. Results In 30mg/L lead treated group calcicum granules were accumulated in bilateral sides of microvessels and plasmalemma endosurface of red blood cells. Meanwhile EDX analysis showed that an obvious peak of lead appeared in calcium granules of outer side of microvessels in rats treated with lead. Conclusion Lead affected blood and circulatory system when blood lead level was about 100μg/L. Its mechanism is related with the changes of calcium distribution. |
| |
| Keywords: | Low level lead Microcirculation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
