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血浆脑钠素水平在病毒性心肌炎患者中的临床意义
引用本文:张春红,沈东,孙红岩,张丽伟,马永江,黄党生. 血浆脑钠素水平在病毒性心肌炎患者中的临床意义[J]. 中华实验和临床病毒学杂志, 2012, 26(2): 125-126
作者姓名:张春红  沈东  孙红岩  张丽伟  马永江  黄党生
作者单位:解放军总医院第一附属医院心内科,北京,100048
摘    要:目的 探讨血浆脑钠素(BNP)水平在病毒性心肌炎(VMC)患者中的临床意义及预后.方法 测定48例病毒性心肌炎患者及40例非心肌炎患者BNP浓度及射血分数(EF),随访2年,观察两组患者,分析血浆BNP与心肌炎的相关性以及BNP对病毒性心肌炎患者预后的影响.结果 VMC组血浆BNP、EF值与对照组比较显著高于对照组(P<0.01,P<0.05).VMC组BNP显著升高患者死亡率高.结论 VMC患者中血浆BNP水平升高,BNP显著升高患者预后差.

关 键 词:利钠肽,脑  心肌炎  心力衰竭,充血性

Prognostic value of brain natriuretic peptide in people with viral myocarditis
ZHANG Chun-hong , SHEN Dong , SUN Hong-yan , ZHANG Li-wei , MA Yong-jiang , HUANG Dang-sheng. Prognostic value of brain natriuretic peptide in people with viral myocarditis[J]. Chinese journal of experimental and clinical virology, 2012, 26(2): 125-126
Authors:ZHANG Chun-hong    SHEN Dong    SUN Hong-yan    ZHANG Li-wei    MA Yong-jiang    HUANG Dang-sheng
Affiliation:. Cardiovascular Department of First Affiliated Hospital to PLA General Hospital, Beijing 100048, China
Abstract:Objective To explore the brain natriuretic peptide (BNP) on prognostic value in patients with viral myocarditis. Methods A total of 48 patients with viral myocarditis and 42 healthy people were enrolled and followed up for two years. The NYHA class and LVEF were recorded and the concentration of BNP were measured. Results The concentration of BNP were higher and EF were lower in patients with viral myocarditis ( P 〈 0.01 ) than contrast people. Higher levels of plasma BNP were related to higher mortality. Conclusion Levels of brain natriuretic peptide measured in the plasma could be a useful biochemical marker for the myocarditis, and high concentration of BNP may correlate with poor prognosis in patients with myocarditis.
Keywords:Natriuretic peptide,brain  Myocarditis  Heart failure,congestive
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