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莫西沙星治疗老年医院获得性肺炎的疗效及安全性评价
引用本文:张中宏,卢献灵,刘冬,李岩. 莫西沙星治疗老年医院获得性肺炎的疗效及安全性评价[J]. 实用诊断与治疗杂志, 2007, 21(1): 23-24
作者姓名:张中宏  卢献灵  刘冬  李岩
作者单位:石河子大学医学院第一附属医院呼吸内科,新疆石河子,832008
摘    要:目的:评价莫西沙星与头孢哌酮/舒巴坦治疗老年医院内获得性肺炎的临床疗效与安全性。方法:将47例老年医院获得性肺炎患者随机分成治疗组27例和对照组20例,分别给予莫西沙星注射液和头孢哌酮/舒巴坦注射液治疗。结果:治疗组与对照组的临床有效率分别为85%和70%,两组对比差异无统计学意义(P〉0.05);治疗组与对照组的细菌学清除率分别为80.1%和76.9%,两组对比差异无统计学意义(P〉0.05);治疗组与对照组的不良反应基本相同。结论:莫西沙星对治疗老年医院获得性肺炎的临床疗效确切、安全性高。

关 键 词:医院获得性肺炎  老年  莫西沙星  头孢哌酮/舒巴坦
文章编号:1672-3457(2007)01-023-02
收稿时间:2006-09-11
修稿时间:2006-09-11

Observation of the clinical effect and safety of avelox in the treatment of nosocomial pneumonia
ZHANG Zhonghong, LU Xianling, LIU Dong, et al. Observation of the clinical effect and safety of avelox in the treatment of nosocomial pneumonia[J]. Journal of Practical Diagnosis and Therapy, 2007, 21(1): 23-24
Authors:ZHANG Zhonghong   LU Xianling   LIU Dong   et al
Abstract:Objective To evaluate the clinical effect and safety in the treatment of nosocomial pneumonia by avelox(moxifloxacin HCL) and Cefperazone-Sulbactam.Methods Forty-seven patients with nosocomial pneumonia were randomly divided into control group(20 cases) by Cefperazone-Sulbactam and treatment group(27 cases) by avelox(moxifloxacin HCL).Results The rate of clinical effect was 85% and 70% in treatment group and control group(P>0.05).The rate of bacteria clearance was 80.1% and 76.9% in treatment and control group(P>0.05).Adverse drug reaction of two groups was nearly the same.Conclusion Avelox(moxifloxacin HCL) is effective and safe for nosocomial pneumonia.
Keywords:Nosocomial pneumonia  avelox(moxifloxacin HCL)  Cefperazone-Sulbactam
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