| 莫西沙星治疗老年医院获得性肺炎的疗效及安全性评价 |
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| 引用本文： | 张中宏,卢献灵,刘冬,李岩.莫西沙星治疗老年医院获得性肺炎的疗效及安全性评价[J].实用诊断与治疗杂志,2007,21(1):23-24. |
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| 作者姓名： | 张中宏 卢献灵 刘冬 李岩 |
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| 作者单位： | 石河子大学医学院第一附属医院呼吸内科,新疆石河子,832008 |
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| 摘 要： | 目的：评价莫西沙星与头孢哌酮／舒巴坦治疗老年医院内获得性肺炎的临床疗效与安全性。方法：将47例老年医院获得性肺炎患者随机分成治疗组27例和对照组20例，分别给予莫西沙星注射液和头孢哌酮／舒巴坦注射液治疗。结果：治疗组与对照组的临床有效率分别为85％和70％，两组对比差异无统计学意义（P〉0．05）；治疗组与对照组的细菌学清除率分别为80．1％和76．9％，两组对比差异无统计学意义（P〉0．05）；治疗组与对照组的不良反应基本相同。结论：莫西沙星对治疗老年医院获得性肺炎的临床疗效确切、安全性高。
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| 关 键 词： | 医院获得性肺炎 老年 莫西沙星 头孢哌酮/舒巴坦 |
| 文章编号： | 1672-3457（2007）01-023-02 |
| 收稿时间： | 2006-09-11 |
| 修稿时间： | 2006年9月11日 |
Observation of the clinical effect and safety of avelox in the treatment of nosocomial pneumonia |
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| ZHANG Zhonghong, LU Xianling, LIU Dong, et al.Observation of the clinical effect and safety of avelox in the treatment of nosocomial pneumonia[J].Journal of Practical Diagnosis and Therapy,2007,21(1):23-24. |
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| Authors: | ZHANG Zhonghong LU Xianling LIU Dong |
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| Abstract: | Objective To evaluate the clinical effect and safety in the treatment of nosocomial pneumonia by avelox(moxifloxacin HCL) and Cefperazone-Sulbactam.Methods Forty-seven patients with nosocomial pneumonia were randomly divided into control group(20 cases) by Cefperazone-Sulbactam and treatment group(27 cases) by avelox(moxifloxacin HCL).Results The rate of clinical effect was 85% and 70% in treatment group and control group(P>0.05).The rate of bacteria clearance was 80.1% and 76.9% in treatment and control group(P>0.05).Adverse drug reaction of two groups was nearly the same.Conclusion Avelox(moxifloxacin HCL) is effective and safe for nosocomial pneumonia. |
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| Keywords: | Nosocomial pneumonia avelox(moxifloxacin HCL) Cefperazone-Sulbactam |
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