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Clinical and laboratory profile of trichinellosis from a non-endemic country
Affiliation:1. Department of Medical Parasitology, PGIMER, Chandigarh, India;2. Department of Paediatrics, PGIMER, Chandigarh, India;1. Department of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, India;2. Department of Orthopedics, All India Institute of Medical Sciences (AIIMS), New Delhi, India;3. Department of Biostatistics, All India Institute of Medical Sciences (AIIMS), New Delhi, India;1. Department of Microbiology, AIIMS, 110029, New Delhi, India;2. Department of Anaesthesia, AIIMS, 110029, New Delhi, India;1. Department of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi, India;2. Department of Hospital Operations, Institute of Liver and Biliary Sciences, New Delhi, India;3. Department of Research, Institute of Liver and Biliary Sciences, New Delhi, India;4. Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India;1. Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Turkey;2. Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Department of Medical Microbiology, Istanbul, Turkey;3. Health Sciences University, Hamidiye Sisli Etfal Educating and Training Hospital, Department of Medical Microbiology, Istanbul, Turkey;4. Istanbul Medipol University, Medical Faculty, Department of Medical Microbiology, Istanbul, Turkey
Abstract:Trichinellosis is a zoonotic parasitic infection caused by nematodes of the genus Trichinella. Humans mostly get infected by eating raw/under-cooked pork. In India, it has been reported mostly as sporadic cases especially from North Eastern and Eastern part of country.In this study, we retrospectively analyzed the socio-demographic pattern, clinical presentation, laboratory profile and treatment response in Trichinella-infected patients visiting our tertiary care center which mainly caters to patients from North India. For this retrospective laboratory-based analysis, patients diagnosed on the basis of positive anti-Trichinella IgG antibodies between 1st June 2008, and 31st May 2019 were included.A total of 11 positive trichinellosis cases were detected, of whom majority were children who presented with history of fever, gastrointestinal symptoms, myalgia, eosinophilia along with hepatomegaly and pulmonary manifestations. No CNS involvement was seen in any of the patients although it is commonly associated with Trichinella infection. All patients recovered uneventfully after antihelminthic treatment.
Keywords:Eosinophilia  Myalgia  Pork  Trichinella  Trichinellosis  Zoonosis
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