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The Polyamine Regulator AMD1 Upregulates Spermine Levels to Drive Epidermal Differentiation
Institution:1. Skin Research Institute of Singapore, Agency for Science, Technology and Research (A1STAR), Singapore, Singapore;2. Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore;3. Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan;4. Centre for Dermatology Research, School of Biology, University of Manchester, Manchester, United Kingdom;5. NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom;6. St John''s Institute of Dermatology, King’s College London, London, United Kingdom;7. Division of Plastic, Reconstructive & Aesthetic Surgery, Department of Surgery, National University Hospital, National University of Singapore, Singapore, Singapore;8. Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA
Abstract:
Keywords:AMD1"}  {"#name":"keyword"  "$":{"id":"kwrd0015"}  "$$":[{"#name":"text"  "_":"adenosyl methionine decarboxylase 1  EGBG"}  {"#name":"keyword"  "$":{"id":"kwrd0025"}  "$$":[{"#name":"text"  "_":"ethylglyoxal bis(guanylhydrazone)  IVL"}  {"#name":"keyword"  "$":{"id":"kwrd0035"}  "$$":[{"#name":"text"  "_":"involucrin  K"}  {"#name":"keyword"  "$":{"id":"kwrd0045"}  "$$":[{"#name":"text"  "_":"keratin  KC"}  {"#name":"keyword"  "$":{"id":"kwrd0055"}  "$$":[{"#name":"text"  "_":"keratinocyte  LOR"}  {"#name":"keyword"  "$":{"id":"kwrd0065"}  "$$":[{"#name":"text"  "_":"loricrin  Put"}  {"#name":"keyword"  "$":{"id":"kwrd0075"}  "$$":[{"#name":"text"  "_":"putrescine  sh"}  {"#name":"keyword"  "$":{"id":"kwrd0085"}  "$$":[{"#name":"text"  "_":"short hairpin  Spd"}  {"#name":"keyword"  "$":{"id":"kwrd0095"}  "$$":[{"#name":"text"  "_":"spermidine  Spm"}  {"#name":"keyword"  "$":{"id":"kwrd0105"}  "$$":[{"#name":"text"  "_":"spermine
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