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Wünderlich Syndrome in Renal Transplant Recipients: A Case Report and Literature Review
Institution:1. Department of Urology, Korea University College of Medicine, Seoul, Republic of Korea;2. Department of Emergency Medicine, Korea University College of Medicine, Seoul, Republic of Korea;3. Department of Urology, Busan Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.;1. Department of Thoracic Surgery, University Medical Center, Ljubljana, Slovenia;2. Department of Pulmonary Diseases and Allergy, University Medical Center, Ljubljana, Slovenia;3. Medical Faculty, University of Ljubljana, Slovenia;4. Center for Intensive Internal Medicine (MICU), University Medical Center, Ljubljana, Slovenia;5. Department of Anesthesiology and Surgical Intensive Therapy, University Medical Center, Ljubljana, Slovenia;1. Division of Abdominal Transplantation, Mayo Clinic, Phoenix, Arizona;2. Transplant Center, Mayo Clinic, Phoenix, Arizona;3. Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona;4. Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona;1. Department of Anesthesiology, Kyushu University Hospital, Fukuoka, Japan;2. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;3. Department of Anesthesiology and Critical Care Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Abstract:BackgroundWünderlich syndrome, or spontaneous atraumatic renal hemorrhage, is a clinical entity rarely described in the native kidney of patients who have undergone renal transplant. Although its manifestation is quite similar in reported cases, it may present few symptoms, from bleeding of unidentified etiology to dramatic pictures associated with hypovolemic shock. There are few reports of spontaneous hemorrhage of a native kidney after kidney transplantation.Case reportWe present a 38-year-old male patient who developed hemorrhage of a ruptured native kidney after a late renal transplantation. We analyze what has been reported in the literature and highlight the possibility of this complication after kidney transplantation. Imaging exams and surgical specimen demonstrated the presence of ruptured angiomyolipoma in the patient's native right kidney. The postoperative period was not complicated, with a benign clinical evolution.ConclusionAlthough rare in patients who have undergone renal transplant, it is justified to suggest Wünderlich syndrome in the presence of acute flank pain, abdominal tenderness, and signs of internal bleeding (Lenk's triad), with unexplained hemoglobin drop.
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