肝癌并阻塞性黄疸介入引流后的近期疗效

目的观察原发性肝癌并阻塞性黄疸行经皮经肝胆道引流术后的近期疗效。方法2005年1月至2009年10月本院16例原发性肝癌并阻塞性黄疸患者行经皮经肝胆道引流术。回顾性统计患者在术前、术后1个月之内转氨酶、白蛋白、胆红素等肝功能指标。并电话随访了全部患者家属以获得生存信息。结果9例患者行胆道内外联合外引流、6例行外引流,1例同时行右肝管内外引流加左肝管外引流。介入术前、后谷丙转氨酶分别是（123.3±69.8）IU/L、（54.1±27.5）IU/L;谷草转氨酶分别是（186.5±149.2）IU/L、（96.8±72.9）IU/L;白蛋白分别是（30.5±3.8）g/L、（27.7±4.3）g/L;总胆红素分别是（368.9±148.1）μmol/L、（218.3±145.7）μmol/L;直接胆红素分别是（272.2±133.2）μmol/L、（141.5±115.7）μmol/L。除白蛋白外,介入手术前后相对应指标之间的差异均具有统计学显著意义（P＆lt;0.05）。患者2月、4月、7月的累计生存率分别为66.7%、22.5%、7.5%。中位生存期3月。结论原发性肝癌并阻塞性黄疸积极行PTBD术,有助于改善患者肝...

Short-term curative effect of percutaneous transhepatic biliary drainage for primary liver cancer with obstructive jaundice

Objective To observe short-term curative effect of percutaneous transhepatic biliary drainage for primary liver cancer（PLC） presenting with obstructive jaundice.Methods 16 cases of primary liver cancer presenting with obstructive jaundice underwent percutaneous transhepatic biliary drainage（PTBD）.Serum transaminase,albumin,bilirubin level of pre-operative and within one month after the operation were analyzed retrospectively.All patients were followed up to acquire survival information by the phone.Results Inner-outer drainage was done in 9 cases,and external drainage in 7.One case underwent inner-outer drainage by right hepatic duct and external drainage by left hepatic duct.Serum alanine aminotransferase,aspartate aminotransferase,albumin,total bilirubin,direct bilirubin were（123.3±69.8） IU/L、（186.5±149.2） IU/L、（30.5±3.8） g/L、（368.9±148.1）μmol/L、（272.2±133.2）μmol/L respectively before the procedure;however,corresponding indexes were（54.1±27.5） IU/L、（96.8±72.9） IU/L、（27.7±4.3）g/L、（218.3±145.7）μmol/L、（141.5±115.7）μmol/L respectively within one month after the procedure.There was significant difference between all indexes of pre-operation and post-operation except the albumin（P〈0.05）.2-,4-and 7-month cumulative survival rates were respectively 66.7%,22.5%,7.5%.Median survival term was three months.Conclusion Active PTBD treatment for PLC with obstructive jaundice helps to improve liver function and prolong survival term.