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Psoriasiform graft-versus-host disease responded to secukinumab: A case report
Authors:Ying Gu PhD  Jing Sun PhD  Jianzhong Zhang MD
Affiliation:1. Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China;2. Department of Dermatology, Peking University People's Hospital, Beijing, China
Abstract:We describe a 9-year-old boy who developed generalised erythematous lesions 12 months after haematopoietic stem cell transplant (HSCT). Histopathology showed both features of psoriasis and graft-versus-host disease (GVHD). The lesions responded well to secukinumab, suggesting that IL-17A monoclonal antibody might be a treatment option for GVHD.
Keywords:graft-versus-host disease  secukinumab  treatment
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