| 胸膜固定术治疗肺癌并发恶性胸腔积液的疗效分析 |
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| 引用本文： | 张燕,孙耕耘. 胸膜固定术治疗肺癌并发恶性胸腔积液的疗效分析[J]. 中华肺部疾病杂志(电子版), 2010, 3(1): 10-13 |
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| 作者姓名： | 张燕 孙耕耘 |
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| 作者单位： | 安徽医科大学第一附属医院呼吸内科,合肥,230022 |
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| 摘 要： | 目的回顾性分析胸膜腔内注入顺铂、高聚金葡素、平阳霉素、胞必佳、肿瘤坏死因子治疗肺癌并发恶性胸腔积液(MPE)的疗效及影响因素。方法对我院2002至2009年确诊肺癌并发MPE共125例患者的临床资料进行分析。结果顺铂组有效率为81.82%,高聚金葡素组为61.90%,平阳霉素组为60.53%,胞必佳组为55.56%,肿瘤坏死因子组为46.67%。除高聚金葡素组外,顺铂组疗效明显高于其他3组(P0.05)。单因素分析显示,疗效受全身应用糖皮质激素、胸水引流方式、胸水部位影响。结论胸膜固定术是治疗肺癌并发MPE的有效方法 ,顺铂疗效最佳。闭式引流较胸穿抽液疗效高,单侧胸水较双侧胸水疗效高(P0.05),全身应用糖皮质激素降低疗效(P0.05)。
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| 关 键 词： | 恶性胸腔积液 硬化剂 影响因素 |
Analysis of the efficacy of treating malignant pleural effusions caused by lung cancer with pleurodesis |
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| ZHANG Yan,SUN Gengyun. Analysis of the efficacy of treating malignant pleural effusions caused by lung cancer with pleurodesis[J]. Chinese Journal of lung Disease（Electronic Edition）, 2010, 3(1): 10-13 |
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| Authors: | ZHANG Yan SUN Gengyun |
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| Affiliation: | ZHANG Yan,SUN Gengyun. (Department of Respiratory Medicine,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)Corresponding author: SUN Gengyun. E-mail:sungengyun@tom.com |
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| Abstract: | Objective To retrospectively analyse the efficacy and the influencing factors of the treatment on lung cancer patients with malignant pleural effusions(MPE) by injecting cisplatin, highly agglutinative staphylococcin, pingyangmycin, nocardia rubra cell wall skeleton and tumor necrosis factor into pleural cavity. Methods The clinical data of 125 lung cancer patients with MPE who were hospitalized in our hospital from 2002 to 2009 was analysed. Results The efficacy of the five kinds of drugs were 81.82%, 61.9... |
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| Keywords: | Malignant pleural effusions Sclerosant Influencing factors |
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