| 炎症相关细胞在动脉粥样硬化发生发展过程中的作用 |
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| 引用本文： | 牟一鸣,傅 蓉,王秋娟,吴玉林.炎症相关细胞在动脉粥样硬化发生发展过程中的作用[J].药学与临床研究,2011,19(2):151-155. |
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| 作者姓名： | 牟一鸣 傅 蓉 王秋娟 吴玉林 |
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| 作者单位： | 中国药科大学生理学教研室,南京,210009 |
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| 摘 要： | 炎症反应为动脉粥样硬化(AS)发生发展过程中的核心因素。与炎症相关的细胞,如血管内皮细胞、单核/巨噬细胞、T淋巴细胞和血管平滑肌细胞,及其分泌的细胞因子与AS的发生、发展密切相关。因此,认识AS病理过程中炎症细胞间的相互作用机制并加以干预,是目前防治AS研究的一个重要方向。
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| 关 键 词： | 动脉粥样硬化 内皮细胞 巨噬细胞 T淋巴细胞 平滑肌细胞 |
| 收稿时间： | 2011/1/5 0:00:00 |
| 修稿时间： | 2011/2/22 0:00:00 |
Roles of Inflammation Related Cells in the Onset and Procession of Atherosclerosis |
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| MOU Yi-ming,FU Rong,WANG Qiu-juan and WU Yu-lin.Roles of Inflammation Related Cells in the Onset and Procession of Atherosclerosis[J].Pharmacertical and Clinical Research,2011,19(2):151-155. |
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| Authors: | MOU Yi-ming FU Rong WANG Qiu-juan and WU Yu-lin |
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| Institution: | MOU Yi-ming,FU Rong,WANG Qiu-juan,WU Yu-lin Department of Physiology,China pharmaceutical University,Nanjing 210009,China |
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| Abstract: | Inflammatory reaction is a key factor on the atherosclerotic course.Inflammation-related cells include vascular endothelial cells,monocyte/macrophage,T lymphocytes and vascular smooth muscle cells.These cells and their secretory cytokines are closely related to the occurrence and development of atherosclerosis.Therefore understanding the interactive mechanisms of inflammatory cells and intervening them are important directions for preventing and treating atherosclerosis. |
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| Keywords: | Atherosclerosis VEC Macrophage T lymphocytes VSMC |
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