LEEP术在宫颈癌前病变应用中的研究进展

近年来,随着宫颈癌筛查水平的不断提高,其发病率逐年下降,但宫颈癌前病变的检出率逐年上升并呈现出年轻化的趋势。如何有效地诊治宫颈癌前病变,成为广大妇科医师极为关注的话题。对于宫颈细胞学检查异常的患者,其处理方式已由单纯的冷刀锥切、电灼到冷冻等手术直至现在的高频电波刀宫颈环切术(Loop electrosurgical excision procedure,LEEP)。LEEP 治疗宫颈上皮内瘤样病变(Cervical intraepithelial neoplasia,CIN)效果已得到广大学者和临床医师认可,治疗也日臻完美,然而随着对此项技术的深入研究,LEEP术在宫颈癌前病变某些诊治环节中不同观点日渐凸显出来,因此本文将主要针对有争议的术后妊娠结局、复发高危因素等进行综述。

The progression of loop electrosurgical excision procedure surgery in cervical precancerous lesions appli- cation

In recent years,with the ongoing cervical cancer screening,the incidence is declining,but the detection rate of cervical precancerous lesions is increasing every year and showing a trend of younger. It is a topic of concern that how to effectively diagnose and treat cervical lesions for general gynecologist. The approachs for patients with abnormal cervical cytology have been undergoing simple cold knife conization, cryosurgery, electro- cantery, laser ablation removal, the Bohm treatment, and loop electrosurgical excision procedure （LEEP）. With the recognizing by the majority of scholars and clinicians on effect of LEEP treatment for cervical intraepithelial neo- plasia -like lesions （CIN）, its technology proliferates and the treatment is also being perfect. However, with the in - depth study of this technology, different view points about LEEP surgery in cervical cancer precancerous lesion diagnosis and treatment aspects increase prominently. This article will focus on controversial pregnancy outcome after recurrence of high - risk factors.