综合干预对稳定期慢性阻塞性肺疾病患者生存质量的影响

目的：探讨综合干预管理对慢性阻塞性肺疾病（COPD）患者肺功能、生活质量的影响。方法选择120例稳定期中重度（Ⅲ、Ⅳ期）COPD 患者为研究对象，随机分为对照组、综合干预组，对照组给予常规治疗，综合干预组在常规治疗的基础上为每例患者建立个人健康档案，对患者进行COPD防治知识讲座、戒烟宣传教育、呼吸功能锻炼、用药指导、心理疏导，时间为12个月，比较2组患者综合干预前后肺功能、SGRQ 评分变化、COPD 急性发作次数、住院天数，每周使用急救药物次数。结果综合干预组 SGRQ 总评分均较管理前下降（P＜0.05），FEV1、FVC、FEV1/Pred%均较入选时无明显变化（P＞0.05），COPD 急性发作次数较对照组减少，差异有统计学意义（P＜0.05）；对照组 FEV1、FEV1/Pred%均较入选时下降、每周使用急救药物次数较干预前增加，差异有统计学意义（均P＜0.05），SGRQ评分较干预前稍下降，差异无统计学意义（P＞0.05）。结论对COPD患者综合干预可以改善患者肺功能，提高患者生存质量，减少COPD急性发作次数。

Effect of standard management on the quality of life on patients with chronic pulmonary disease

Objective To evaluate the effect of combined management on the quality of life on patients with chronic pulmonary disease. Methods 120 patients were collect from clinic service or sickroom in our hospital and were divided into two treatment groups randomly. We carry out lectures, propaganda on smoke quitting to guide exercise of respiratory function and medicine taking, et al. The pulmonary function, the score of SGRQ, the times of acute episode times, the hospital day, the number of use emergency medicine, that were measured before and after a 12 months intervention. Results Twelve months later, in the combined management group, The SGRQ significantly was lowered （P＆lt;0.05）, the times of acute episode has decreased（P＆lt;0.05）, and the FEV1, FVC, FEV1/Pred%has not decreased（all P＆gt;0.05）. The times of acute episode has decreased（P＆lt;0.05）, and the number of use emergency medicine has decreased（P＆lt;0.05）. While in control group, the FEV1, FVC, FEV1/Pred%all decreased（all P＆lt;0.05）, and the number of use emergency medicine has increased（P＆lt;0.05, and the SGRQ has decreased（P＆gt;0.05）. Conclusion For patients with chronic pulmonary disease, standard management can improve the pulmonary function, and improve the quality of life, as well as decrease the times of acute episode.