中央区脑膜瘤患者的功能性近红外光学成像分析及文献回顾

目的评价中央区脑膜瘤患者和对照组手指运动相关的脑激活部位之区别,探讨脑功能重组的机制。方法对1例脑膜瘤患者和2例对照进行近红外脑功能成像检查。试验采用模块设计、单手对指任务,经数据处理、统计和脑功能区定位,比较患者和对照激活区域的差别。结果对照组进行单手运动时对侧大脑半球运动区激活,脑膜瘤患者右手运动时左侧初级感觉运动皮层激活,而左手运动时右侧半球（患侧）在肿瘤后外侧初级感觉运动皮层的通道出现较弱激活,而左侧半球（健侧）初级感觉运动皮层、补充运动区、运动前区出现较强激活。结论功能性近红外脑功能成像检查可检测中央区脑肿瘤患者手部运动相关的脑功能重组。

Functional near infrared spectroscopy imaging of motor-related cortex activation in a patient with ~ meningioma located in central sulcus and literature review

Objective To evaluate the hand movement related cortex activation in a patient with menigioma located in central sulcus and in control using functional near infrared spectroscopy （iNIRS）. Methods We employed fNIRS to evaluate cortical activation with unilateral hand movement in a patient with meningioma and 2 controls. Block design of finger movement task was used. The activated channles were compared between the patient and controls. Results Activation in motor area in contralateral hemisphere were found during unilateral hand movement. Activation in contralateral primary sensorimotor cortex（PSMC） were found during right hand movement in the patient. Activation was found in right PSMC （area posterolateral to the tumor） and was weak during left hand movement. Simultanoesly, activation in left PSMC, supplementary motor area（SMA） and premotor cortex（PMC） were relatively stronger. Conclusion Cortical reorganization can be detected by fN/RS in patient with brain tumor in central sulcus.