| SASH1基因研究进展 |
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| 引用本文： | 刘秋菊,贺远龙,许琳,赵丽萍,王青.SASH1基因研究进展[J].中华临床医师杂志(电子版),2013(22):161-163. |
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| 作者姓名： | 刘秋菊 贺远龙 许琳 赵丽萍 王青 |
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| 作者单位： | 青岛大学医学院附属青岛市市立医院东院消化科,山东省266071 |
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| 基金项目： | 国家自然科学基金青年科学基金资助项目（81101813） |
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| 摘 要： | SASH1（SAM-and SH3-domain containing 1）基因是进化保守的SLY基因家族的一员，广泛表达于人体多种正常组织（淋巴样干细胞除外）。其可通过调节细胞生长、增殖和凋亡等，参与多种疾病的发生发展。本文对SASH1基因的分子结构、功能、调节通路及与肿瘤等疾病的关系作一综述。
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| 关 键 词： | 信号传导 肿瘤 综述文献（主题） SASH1基因 |
Research progress of SASH1 gene |
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| LIU Qiu-ju,HE Yuan-long,XU Lin,ZHAO Li-ping,WANG Qing.Research progress of SASH1 gene[J].Chinese Journal of Clinicians(Electronic Version),2013(22):161-163. |
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| Authors: | LIU Qiu-ju HE Yuan-long XU Lin ZHAO Li-ping WANG Qing |
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| Institution: | . Department of Gastroenterology, Qingdao Municipal Hospital Affiliated to Qingdao University Medical College, Qingdao 266071, China |
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| Abstract: | SASH1 gene, a member of the evolutionarily conserved SLY-family, is widely expressed in normal human tissue, with the exception of lymphoblastoid cells. SASH1 gene played an important role in the development and progression of various diseases by regulating the cell growth, proliferation and apoptosis. The molecular structure, function, regulation passageway and the relationship with tumors of SASH1 gene have been detailed reviewed. |
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| Keywords: | Signal transduction Neoplasms Review literature as topic SASH1 gene |
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