急性心肌梗塞血清磷酸肌酸激酶的研究

急性心肌梗塞的梗塞范围大小与临床并发症、预后密切相关。梗塞范围越大,并发症越多,预后越严重。本文通过对102例急性心肌梗塞血清磷酸肌酸激酶(CK)与梗塞部位,临床并发症及预后关系的分析,结果表明有严重并发症者的CK峰值显著高于无并发症者(P<0.01),住院死亡者的CK峰值显著高于存活者(P<0.01),广泛前壁梗塞者显著高于前间壁梗塞者(P<0.01)。CK与CK—MB峰值间呈高度正相关(r=0.91)。因此,CK峰值大小是估计梗塞范围,提示预后的敏感和可靠指标。

Study on Serum Creatine Kinase of Patients with Acute Myocardial Infarction

Intimate relations are known to exist among the extent of infarction , its complication and the prognosis. The bigger extent of infarct the more the complications and poorer the prognosis will be. Results of our analysis of relations among serum creatine kinase (CK),site of infarction, clinical complication and prognosis in 102 cases of acute myocardial infarction showed that the CK peak value was much higher in those with,severe complication than those whithout (p<0.01),those died in hospital have a CK peak value significantly higher than that of surviors (p<0.01), and those with extensive anterier wall infarct have much higher CK peak value than those with anterier septol wall infarction (p<0.01). A highly positive correlation was found between CK and CK-MB peak value (r=0.91). It is thus'suggested that the CK peak value is a sensitive and reliable index in estimation of extent of infarction and prediction of prognosis.