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PI3K与支气管哮喘发作期T细胞增殖周期蛋白关系的研究进展
引用本文:房洁,王鸿程. PI3K与支气管哮喘发作期T细胞增殖周期蛋白关系的研究进展[J]. 国际呼吸杂志, 2008, 28(12): 751-754
作者姓名:房洁  王鸿程
作者单位:泸州医学院附属医院呼吸内科,646000
基金项目:四川省卫生厅资助项目 
摘    要:T细胞是支气管哮喘(简称哮喘)发病机制中的核心细胞.T细胞增殖周期异常在哮喘中发挥着重要作用.PI3K信号转导途径是T细胞内重要的信号转导途径,与细胞周期蛋白异常密切相关,其机制的研究对于哮喘的治疗有重要的意义.

关 键 词:哮喘  T细胞  细胞周期蛋白

Advances on relationship of phosphoinositide 3-kinase pathway with cell generation cyclin in T lymphocytes of patients with acute asthma
FANG Jie,WANG Hong-cheng. Advances on relationship of phosphoinositide 3-kinase pathway with cell generation cyclin in T lymphocytes of patients with acute asthma[J]. International Journal of Respiration, 2008, 28(12): 751-754
Authors:FANG Jie  WANG Hong-cheng
Abstract:T lymphocyte is the core cell in the bronchial asthma(asthma)nosogenesis.The abnormal T lymphocyte generation cycle has an important role in the asthma.The phosphoinositide 3-kinase pathway is the important signal transduction pathway in the T lymphocyte and has an important relation with the abnormal core cell.The research is very interesting to the asthma treatment.
Keywords:PI3K
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