| 药理效应法筛选中药细辛活性组群的试验研究 |
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| 引用本文： | 张会宗,孟莉,刘晶,向绍杰,乔敏,李国信.药理效应法筛选中药细辛活性组群的试验研究[J].实用中医内科杂志,2009,23(8):29-30. |
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| 作者姓名： | 张会宗 孟莉 刘晶 向绍杰 乔敏 李国信 |
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| 作者单位： | 辽宁省中医药研究院,辽宁沈阳,110034 |
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| 基金项目： | 辽宁省教育厅支持项目 |
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| 摘 要： | 目的]评价细辛不同组份止咳、祛痰作用。方法]以止咳、祛痰实验为考查指标,对不同溶解度参数溶剂提取的细辛提取物进行药效学考查。结果]细辛不同提取物均能显著延长咳嗽潜伏期,具有明显的止咳作用(P<0.01),但祛痰效果不显著(P>0.05)。结论]挥发油提取物为细辛止咳作用的主要物质基础。
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| 关 键 词： | 细辛 止咳 祛痰 药理效应法 |
Screening Active Ingredient of Herba Asari by Pharmacology Effect Method |
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| Authors: | Zhang Hui-zong Meng Li Liu Jing Xiang Shao-jie Qiao Min Li Guo-xin |
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| Institution: | Zhang Hui-zong Meng Li Liu Jing Xiang Shao-jie Qiao Min Li Guo-xin |
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| Abstract: | Objective] To study the effects of various ingredients in Herba Asari on stopping coughing and eliminating phlegm. Method] Using antitussive and expectorant experiments as index to estimate pharmacodynamics actions of the extracted from Herba Asari in different solubility of solvents. Results] The extracted from Herba Asari could prolong the latent period of cough significantly and had good effects on stopping coughing(P <0.01). But they had no evident expectorant effects (p>0.05). Conclusion] Volatile oil extracted from Herba Asari is essential material foundation for antitussive effect. |
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| Keywords: | Pharmacology effect method Herba Asari Stopping coughing Eliminating phlegm |
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