院内真菌感染因素及治疗的调查分析

目的了解我院院内真菌感染的临床特点,为预防和减少院内真菌感染提供依据。方法对2002年10月~2004年9月出院患者真菌培养阳性病例进行回顾性分析。结果院内真菌感染患者107例,占同期院内感染的19%,好发于呼吸道(81.3%)、消化道(14.0%)、泌尿道(10.3%),多发于老年人占(71%),真菌以白色念珠菌居多(92.5%),与原基础疾病、不合理应用抗菌药物有关;抗真菌治疗不规范。结论合理应用抗菌药物是预防和减少院内菌感染的关键,规范临床抗真菌治疗方法是真菌感染预后的重要手段。

Analysis of factors and treatment of nosocomial fungal infection

OBJECTIVE To investigate the clinical features of nosocomial fungal infection,offering the bases in order to prevent and reduce the occurrence of nosocomial fungal infection.METHODS The fungus-cultured positive cases among the discharged patients from October 2002 to September 2004 were reviewed and analyzed.RESULTS There were 107 patients with nosocomial fungal infection,which accounted for 19% of all nosocomial infections in the same period.The predilection sites were respiratory tract(81.3%) and digestive(14.0%) and urinary(10.3%).The main pathogen was Candida albicans(92.5%),nosocomial mycosis correlated with the serious underlying diseases,irrational use of antibiotics and nonstandard treatment of antifungus.CONCLUSION Rational use of antibiotics is the most important way to prevent and reduce nosocomial fungal infection,and standardize the ways of anti-fungus treatments.