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子宫内膜功能亢进性疾病的“异病同治”诊治研究思路
引用本文:张绪丹,师伟,张芳,石雅馨,葛晓晨,王雁飞,刘双,徐丽.子宫内膜功能亢进性疾病的“异病同治”诊治研究思路[J].世界科学技术-中医药现代化,2021,23(12):222-227.
作者姓名:张绪丹  师伟  张芳  石雅馨  葛晓晨  王雁飞  刘双  徐丽
作者单位:山东中医药大学中医学院 济南 250014,山东中医药大学附属医院 济南 250014,山东中医药大学中医学院 济南 250014,山东中医药大学中医学院 济南 250014,山东中医药大学中医学院 济南 250014,山东中医药大学中医学院 济南 250014,山东中医药大学中医学院 济南 250014,山东大学附属省立医院 济南 250021
基金项目:山东省教育厅泰山学者工程(tsqn201909185),负责人:师伟;山东省科学技术厅重大科技创新项目(2018CXGC1309):基于多维谱—效联合 网络药理学关键技术的桂枝茯苓丸治疗子宫腺肌病的物质基础研究,负责人:师伟;国家自然科学基金委员会面上项目(81873330):基于 Rho/ROCK信号通路的桂楼药对宫腔缓释给药降低子宫腺肌病异位内膜细胞侵袭力的研究,负责人:师伟。
摘    要:笔者根据现代临床子宫内膜的病理演变过程结合中医“异病同治”理念,提出“子宫内膜功能亢进性疾病”概念,涵盖5种常见的子宫内膜疾病:无排卵性异常子宫出血(Abnormal Uterine Bleeding Ovulatory dysfunction,AUB-O),子宫内膜息肉(Endometrial Polyp,EP),子宫内膜异位症(Endometriosis,EMs),子宫腺肌病(Adenomyosis,AM),子宫内膜癌(Endometrial Carcinoma,EC)。基于文献的汇总,分析得到此类疾病的子宫内膜病理演变与中医病因病机的关联性,为寻找关键通路、创新性治疗此类疾病提供了重要的参考方向,对深化中医妇科学常见疾病的共性病因病机提供了理论依据和探索思路。

关 键 词:子宫内膜息肉  子宫内膜癌  子宫腺肌病  子宫内膜异位症  排卵障碍型异常子宫出血  异病同治
收稿时间:2021/6/2 0:00:00
修稿时间:2022/1/19 0:00:00

Diagnosis and Treatment Research Ideas of Endometrial Hyperfunction Disorders with "Same Treatment for Different Diseases"
Zhang Xudan,Shi Wei,Zhang Fang,Shi Yaxin,Ge Xiaochen,Wang Yanfei,Liu Shuang and Xu Li.Diagnosis and Treatment Research Ideas of Endometrial Hyperfunction Disorders with "Same Treatment for Different Diseases"[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2021,23(12):222-227.
Authors:Zhang Xudan  Shi Wei  Zhang Fang  Shi Yaxin  Ge Xiaochen  Wang Yanfei  Liu Shuang and Xu Li
Institution:Shandong University of Traditional Chinese Medicine, Jinan 250014, China,The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250012, China,Shandong University of Traditional Chinese Medicine, Jinan 250014, China,Shandong University of Traditional Chinese Medicine, Jinan 250014, China,Shandong University of Traditional Chinese Medicine, Jinan 250014, China,Shandong University of Traditional Chinese Medicine, Jinan 250014, China,Shandong University of Traditional Chinese Medicine, Jinan 250014, China,Provincial Hospital Affiliated to Shandong University, Jinan 250021, China
Abstract:The author proposed the concept of "endometrial hyperfunctional diseases" based on the pathological evolution of endometrium in modern clinical practice and the concept of "same treatment for different diseases" in Chinese medicine. The concept of "endometrial hyperfunctional diseases" is proposed. It covers five common endometrial diseases: Abnormal Uterine Bleeding Ovulatory dysfunction (AUB-O), Endometrial Polyp (EP), Endometriosis (EMs), Adenomyosis (AM), and Endometrial Carcinoma (EC). Based on the summary of the literature, this paper analyzed the relevance of the endometrial pathological evolution of such diseases to the TCM etiology and pathogenesis. This provides an important reference direction for the search of key pathways and innovative treatment of such diseases. It also provides a theoretical basis and exploration of ideas for deepening the common etiology and pathogenesis of common diseases in TCM gynecology.
Keywords:Endometrial polyp  Endometrial carcinoma  Adenomyosis  Endometriosis  Abnormal uterine bleeding ovulatory dysfunction  Same treatment for different diseases
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