从炎症细胞因子浅析血栓性浅静脉炎病因病机及治疗经验＊

血栓性浅静脉炎为皮下浅静脉炎症性血栓性疾病,属中医“青蛇毒”“赤脉”“恶脉”等范畴,临床证型多分为湿热内阻型、瘀血阴滞型,不同证型之间炎性细胞因子表达不同,湿热内阻型多处在疾病急性期,伴随炎性细胞因子大量释放,瘀血阴滞型多处在疾病慢性期,炎性细胞因子相对减少。本研究旨在从炎症细胞因子出发,论证血栓性浅静脉炎的病因病机,及其与中医辨证分型的关系,从理论探析,从而指导用药。

A Brief Analysis on Etiology and Pathogenesis and Treatment Experience of Superficial Thrombophlebitis from Inflammatory Cytokines

Superficial thrombophlebitis is an inflammatory thrombotic disease of the superficial subcutaneous veins, which belongs to the categories of "green snake venom", "red veins" and "evil veins" in traditional Chinese medicine. And its clinical syndrome types are mostly divided into damp-heat internal resistance type and blood stasis yin-stagnation type, and the expressions of inflammatory cytokines vary between different syndrome types. The damp-heat internal resistance type is mostly in the acute stage of the disease, accompanied by the release of a large amount of inflammatory cytokines, and the blood stasis yin-stagnation type is mostly in the chronic stage of the disease, with relatively reduced inflammatory cytokines. This study aims to demonstrate the etiology and pathogenesis of superficial thrombophlebitis and its relationship with TCM syndrome differentiation from the perspective of inflammatory cytokines, and to analyze theoretically to guide medication.