静脉注射胺碘酮终止心肌炎患儿异位性心动过速的疗效观察

探讨胺碘酮治疗小儿病毒性心肌炎心律失常的疗效及安全性以及治疗前后心脏内分泌的改变情况。对 1 31例病毒性心肌炎急性期患儿并发心律失常者在心电监护下静脉注射 (简称静注 )胺碘酮。并在静注胺碘酮前后分别测定血浆心钠素 (ANP) ,心脏指数 (CI)。结果 :总转复率为 87.79% ,室上性心动过速的患儿转达复率为 90 .80 % ,室性心动过速的患儿转复率为 81 .82 % ,室上性、室性心动过速的转复率比较 ,差异无显著性。各种心律失常发作时患儿血浆心钠素ANP明显高于正常对照组和转复后 ,CI则明显低于正常对照组和转复后 (P <0 .0 5 )。其间无一例病情恶化者。结论 :胺碘酮是一个治疗小儿心肌炎心律失常的安全有效的药物 ,但部分患儿对该药物不甚敏感。

Effects of Amiodarone Intravenous Injection on Tachycardia in Patients With Myocarditis

To observe the effects of amiodarone intravenous injection on tachycardia in patients with myocarditis,131 patients with myocarditis were intravenously injected amiodarone when tachycardia occurred and the plasma natriuretic polypetide(ANP) and cardiac index(CI) were measured before,during and after tachycardias occurred .Result:The total successful rate of amiodarone cardioversion on tachyarrhy thmias was 87.79%,the effective rate of super ventricular and ventricular tachycardias(SVT,VT) were 90.80% and 81.82%,respectively,When tachycardias occurred the patients had a significant higher ANP and a lower CI than before tachycardia occurred and after tachycardias determination.Conclusion: Amiodarone is an effective and safety agent for the treatment of tachycardia due to myocaditis.