高压氧对血管性痴呆患者认知和生活能力及血液流变学的影响

目的：观察高压氧（HBO）治疗血管性痴呆（VD）的临床疗效及对血液流变学的影响。方法：VD患者72例,分为HBO组和对照组各36例,均按脑血管病常规治疗,并口服控制血压、血糖的药物,预防并发症的发生。HBO组患者同时配合HBO治疗。治疗前后采用简明智力量表（MMSE）及ADL评定患者的认知功能和ADL,并进行血液流变学检测。结果：治疗12周后,MMSE评分,2组均较治疗前有明显提高,HBO组更明显;ADL评分,HBO组较治疗前及对照组明显上升;血液流变学比较,HBO组血浆黏度、全血高切、低切还原黏度,红细胞压积、沉降率及聚集指数均较治疗前及对照组明显下降（均P〈0.05,0.01）,对照组ADL及血液流变学治疗前后差异无统计学意义。结论：HBO可提高血管性痴呆患者的认知功能和ADL能力,改善血液流变学指标。

Effect of Hyperbaric Oxygen on Cognition and Activity of Daily Life and Hemorheology of Patients with Vascular Dementia

Objective: To observe the clinical effectiveness of hyperbaric oxygen for vascular dementia(VD) and its influence on hemorheology.Methods: Sixty-four cases of VD were randomly divided into hyperbaric oxygen group(n=36) and control group(n=28).The hemorheology was checked before and 12 weeks after treatment.By using Mini-mental state examination(MMSE) and Activity of Daily Living(ADL) indexes,the effects were graded and compared.Results: After treatment,MMSE and ADL indexes in hyperbaric oxygen group were im...