Combined radical prostatectomy and abdominoperineal resection for locally invasive rectal cancer |
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Authors: | Daniel Fernández-Martínez Antonio Rodríguez-Infante Elsa Castelo-álvarez Iván Fernández-Vega Miguel Suárez-Hevia Nuria Truán-Alonso Ricardo F. Baldonedo-Cernuda José A. álvarez-Pérez Herminio Sánchez-Farpón |
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Affiliation: | aUnit of Coloproctology, Department of General and Digestive Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain;bDepartment of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain;cDepartment of Urology, Hospital Universitario Central de Asturias, Oviedo, Spain |
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Abstract: | INTRODUCTIONAn infiltration of urological organs is found in 5–10% of patients with colorectal carcinoma. Total pelvic exenteration is the standard procedure for locally advanced rectal cancer. In selected patients with rectal cancer involving the prostate or seminal vesicles, the bladder can be preserved and en bloc radical prostatectomy with abdominoperineal rectal resection can be performed. We report two patients who treated with this combined approach.PRESENTATION OF CASETwo patients with symptoms of rectal bleeding and pelvic pain were investigated. Colonoscopy demonstrated a tumor in the lower rectum. Biopsies revealed adenocarcinoma. Both pelvic MRI and endorectal ultrasound showed tumors that invaded the prostate and the seminal vesicles directly but without invasion of the bladder. After neoadjuvant chemoradiation, combined radical prostatectomy and abdominoperineal amputation was performed. None has developed local recurrence, but one of them was operated on for a single lung metastasis. After a follow-up of 28 and 20 months, respectively, the patients are alive without evidence of local recurrence or distant disease.DISCUSSIONThis procedure obviates the need for urinary diversion without compromising the local tumor control. Intraoperative and postoperative diagnostic difficulties, and clinical aspects in relation to postoperative anastomotic leak and survival of patients are discussed.CONCLUSIONEn bloc radical prostatectomy and proctosigmoidectomy is feasible in selected patients with rectal cancer and invasion limited to the prostate or seminal vesicles because it provides good local tumor control and significantly improves the patient''s quality of life in comparison to total pelvic exenteration. |
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Keywords: | Rectal cancer Locally advanced rectal cancer Radical prostatectomy Abdominoperineal resection |
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