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脐血风疹抗体滴度与新生儿听力的关系探讨
引用本文:王幼勤,徐素琴,徐艳华,胡科丽,李斐. 脐血风疹抗体滴度与新生儿听力的关系探讨[J]. 贵州医药, 2000, 24(4): 209-210
作者姓名:王幼勤  徐素琴  徐艳华  胡科丽  李斐
作者单位:1. 贵州省人民医院,贵阳,550002
2. 贵州省人民医院,新生儿科,贵阳,550002
3. 贵州省人民医院,妇产科,贵阳,550002
摘    要:目的 通过比较风疹流行期组与非流行期组新生儿脐血风疹抗体滴度及两组新生儿听性脑干诱发电位(ABR)结果,了解孕期风疹病毒感染与胎儿听功能的影响。方法 采用酶联免疫吸附法测试流行期组53例,非流行期组10例新生儿脐血风疹特异性抗体IgG滴度;测试两组新生儿共45例(90耳)ABR。结果 流行期组脐血RV-IgG滴度阳性率86.8%,明显高于非流行期组20%的阳性率,P〈0.01;流行期组ABR异常检

关 键 词:风疹抗体滴度 脐血 RV-IgG ABR 新生儿 听力

The relationship on the rubella antibody titer of cord blood with infants audition
Wang Youqin,Xin Shuqin,Xiu Yanhua,et al.. The relationship on the rubella antibody titer of cord blood with infants audition[J]. Guizhou Medical Journal, 2000, 24(4): 209-210
Authors:Wang Youqin  Xin Shuqin  Xiu Yanhua  et al.
Affiliation:Wang Youqin,Xin Shuqin,Xiu Yanhua,et al. Guizhou Provincial People's Hospital,Guiyang 550002
Abstract:Objective To study relationship of the rubella infection with the neonate auditus and influence effect. Methods RV-IgG of neonate from blood of 53 cases cord rubella epidemic term and 10 cases from unepidemic term were assayed by ELISA. Also ABR was determined in 45 infants. Results The positive rates of RV-IgG in epidemic group and unepidemic were 86.8% and 20% respectively(P<0.01).The detectable rates of abnormat ABR was 35.7% in epidemic group, but unepidemic group was negative (P<0.01). Conclusion The rubella virus infection can cause the inner ear developmental disturbance of fetuse. The cause of congenital rubella deafness can be found early by determine the RV-IgG antibody titer of cord blood.
Keywords:Rubella Cord blood RV-IgG ABR Infantion
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