我院90例药物不良反应/事件分析

目的:探讨我院药物不良反应(ADR)发生的特点,为临床合理用药及药品安全性评价提供参考。方法:对我院2012年收集到的90例有效ADR报告进行统计分析。结果:90例ADR报告中,66例19⁶5岁患者发生ADR,占73.33%;静脉注射给药引发的ADR 43例,占47.78%;最易引起ADR的药物为中药制剂41例,占49.38%,其次为抗感染药物19例,占21.11%;ADR损害类型主要以皮肤及其附件损害为主(32例,占36%);新的ADR 32例,主要为中药制剂引发;严重ADR9例,其中皮肤及其附件损害为6例。结论:临床应重视和加强ADR监测,合理用药,减少ADR的发生。

Retrospective analysis of 90 ADR/ADE reports in our hospital

Objective： To explore the characteristics of adverse drug reactions （ADRs） in our hospital in order to provide reference for clinical rational use and safety evaluation of drugs. Methods： We collected 90 cases of ADRs reports in our hospital in 2012 and do statistical analysis. Results： ADRs occurred in 73.33% of patients（66 of 90） aged 19 to 65; ADRs caused by intravenous injection were 47.78% （43 of 90 cases） of patients; the most likely ADRs were caused by traditional Chinese medicines （41 cases, accounting for 49.38%）, followed by antiinfective drugs （19 cases, 21.11%） ; the main types of ADRs were damage to the skin and its appendents （32 cases, accounting for 36%） ; There were 32 new ADRs which were mainly related with traditional Chinese medicines; There were 6 cases of damage to the skin and its appendents （66.67%） of 9 cases of serious ADRs. Conclusion： We should pay attention to and strengthen ADR monitoring and rational use of drugs for reducing or avoiding the occurrence of ADRs.