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心肾综合征的临床挑战
引用本文:吴光哲,王岩,贾建华. 心肾综合征的临床挑战[J]. 心血管病学进展, 2011, 32(3): 382-385. DOI: 10.3969/j.issn.1004-3934.2011.03.024
作者姓名:吴光哲  王岩  贾建华
作者单位:中国人民解放军第406医院,辽宁,大连116041
摘    要:近年来心肾疾病之间的关系引起了广泛关注,慢性肾脏病与心血管病两者有共同的发病因素、互为危险因素。心肾综合征(CRS)是指心脏或肾脏功能不全时相互影响、相互加重导致心肾功能急剧恶化的一种临床综合征。尽管目前在CRS研究中取得了一些进展,但对CRS的发病机制尚未完全阐明,现有的一些治疗效果不理想,尚未形成共识。因此,还需进一步加强CRS病理生理学机制研究,确定靶向治疗策略,从而阻断心-肾恶性循环。

关 键 词:心肾综合征  发病机制  生物标志物  治疗策略

Clinical Challenge of Cardiorenal Syndrome
WU Guang-zhe,WANG Yan,JIA Jian-hua. Clinical Challenge of Cardiorenal Syndrome[J]. Advances in Cardiovascular Diseases, 2011, 32(3): 382-385. DOI: 10.3969/j.issn.1004-3934.2011.03.024
Authors:WU Guang-zhe  WANG Yan  JIA Jian-hua
Affiliation:WU Guang-zhe1,WANG Yan1,JIA Jian-hua1,YAN Cheng-hui2(1.No.406 Hospital of the PLA,Dalian 116041,Liaoning,China,2.The Cardiovascular Research Institute and Department of Cardiology,Shenyang General Hospital,Shenyang Military Command Area,Shenyang 110016,China)
Abstract:The relationship between renal and cardiac diseases has been closely examined in recent years.Specifically,cardiorenal syndrome(CRS) can be defined as a clinical syndrome in which the heart or the kidney fails to compensate for the functional impairment of the other organ,which in turn results in a decline in function for both organs.Despite recent recognition of CRS,the underlying pathophysiology is not well understood,and no consensus has been reached for its management.This review recommends that further...
Keywords:cardiorenal syndrome  pathogenesis  drug therapy  
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