| 载脂蛋白AV与血脂代谢研究新进展 |
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| 引用本文： | 胡璐. 载脂蛋白AV与血脂代谢研究新进展[J]. 心血管病学进展, 2011, 32(3): 397-400. DOI: 10.3969/j.issn.1004-3934.2011.03.029 |
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| 作者姓名： | 胡璐 |
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| 作者单位： | 中南大学湘雅二医院,湖南长沙,410011 |
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| 摘 要： | 新发现的载脂蛋白AV参与血脂代谢,尤其是在三酰甘油分解代谢中起重要作用。载脂蛋白AV通过减少脂蛋白的生成率、增强脂蛋白脂酶对三酰甘油的水解,促进低密度脂蛋白受体介导的富含三酰甘油的脂蛋白颗粒清除作用来调节血脂代谢。载脂蛋白AV的基因多态性与心血管疾病的发生有着密切的关系。
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| 关 键 词： | 载脂蛋白AV 三酰甘油 基因多态性 脂蛋白脂酶 低密度脂蛋白受体 |
Apolipoprotein AV and Metabolism of Blood Lipids |
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| HU Lu. Apolipoprotein AV and Metabolism of Blood Lipids[J]. Advances in Cardiovascular Diseases, 2011, 32(3): 397-400. DOI: 10.3969/j.issn.1004-3934.2011.03.029 |
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| Authors: | HU Lu |
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| Affiliation: | HU Lu1,ZHAO Shui-ping2(1.2009 Graduate,Department of Cardiology,The Second Xiangya Hospital of Central South University,Changsha 410011,Hunan,China,2.Department of Cardiology,China) |
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| Abstract: | Apolipoprotein AV,a newly discovered apolipoprotein,has been shown to play an important role in the metabolism of lipids.It is especially relevant to the metabolism of triglycerides primarily through reducing the lipoprotein production rate,stimulating hydrolysis of triglycerides by lipoprotein lipase,and facilitating clearance of triglyceride-rich lipoprotein by low-density lipoprotein receptor.It has been found that the polymorphism of apolipoprotein AV is closely related with coronary heart disease.This ... |
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| Keywords: | apolipoprotein AV triglyceride polymorphism lipoprotein lipase low-density lipoprotein receptor |
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