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| 鹿茸口服液对抗氧化酶的影响 | |
| 引用本文： | 王立军,陈晓光,朴宪.鹿茸口服液对抗氧化酶的影响[J].中药药理与临床,2004,20(2):33-34. |
| 作者姓名： | 王立军 陈晓光 朴宪 |
| 作者单位： | 1. 北京大学深圳医院药剂科,深圳,518036 2. 吉林省中医中药研究院,长春,130021 3. 延边州药检所 |
| 摘 要： | 目的:研究鹿茸口服液对青年及老年小鼠的抗氧化作用.方法:灌服鹿茸口服液后,测定小鼠SOD、CAT和GSHpx活性及MDA含量.结果:鹿茸口服液对老年小鼠SOD活性增强和MDA含量降低作用均明显强于对青年小鼠,并能增强老年小鼠肝CAT和GSHpx活性.结论:鹿茸口服液对老年小鼠具有抗氧化作用. |
| 关 键 词： | 鹿茸口服 鹿茸 超氧化物歧化酶 氧化氢酶 胱甘肽氧化酶 丙二醛 抗氧化 |
Effect of Pilose antler oral liquid(PAOL) on antioxidant enzymes and MDA |
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| Wang Lijun,Chen Xiaoguang ,Piao Xian.Effect of Pilose antler oral liquid(PAOL) on antioxidant enzymes and MDA[J].Pharmacology and Clinics of Chinese Materia Medica,2004,20(2):33-34. | |
| Authors: | Wang Lijun Chen Xiaoguang Piao Xian |
| Institution: | Wang Lijun,Chen Xiaoguang 1,Piao Xian 2 |
| Abstract: | Objective: To investigate the antioxidant effect of PAOL on young and old mice. Methods: The activity of superoxide dismutase(SOD) , catalase(CAT) ,glutathione peroxidase(GSHpx) and content of malondialdehyde(MDA) were measured after PAOL given to mice. Results: The enhancement of SOD activity and decrease of MDA content in brain, liver and kidney tissues were observed in old mice(24 months) than young mice(1 month) after PAOL had been administrated orally for 10 successive days at dose of 4.0g/kg. In additon,PAOL could increase the activity of CAT and GSHpx in old mice. Conclusion: PAOL exhibits antioxidant effect on old mice. |
| Keywords: | Pilose antler oral liquid(PAOL) SOD Cat GSHPx MDA antioxidant effect |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |