系统性护理干预对晚期非小细胞肺癌化疗患者癌因性疲乏的影响

目的：探讨系统性护理干预对改善晚期非小细胞肺癌（ NSCLC）化疗患者癌因性疲乏的效果。方法采用随机数字表法将80例晚期NSCLC化疗患者分为干预组和对照组，每组各40例。对照组根据医嘱行肿瘤内科患者常规护理，干预组在此基础上进行系统的癌因性疲乏护理干预。应用简易疲乏评估表和FACT-L（V3．0）量表分别在干预前、干预15 d后对两组患者进行癌因性疲乏和生存质量评估。结果共发放问卷80份，回收有效问卷80份，有效回收率100％。干预前两组患者疲乏程度及生存质量得分比较差异无统计学意义（P＞0．05）。干预后干预组患者的癌因性疲乏程度较对照组明显降低（χ2＝8．47，P＝0．04）。干预组患者生理状况、社会/家庭状况、与医生的关系、情感状况、功能状况、附加的关注情况及量表总分分别为（32．15＆#177;6．08），（35．31＆#177;5．33），（12．38＆#177;2．67），（28．59＆#177;4．53），（34．34＆#177;5．86），（43．80＆#177;7．76），（186．57＆#177;32．23）分，分别高于对照组的（25．45＆#177;5．42），（28．68＆#177;4．16），（9．95＆#177;1．49），（21．87＆#177;3．95），（26．21＆#177;5．01），（36．63＆#177;8．24），（148．79＆#177;28．27）分，差异均有统计学意义（t值分别为5．20，6．20，5．03，7．07，6．67，4．01，5．57；P＜0．01）。结论在常规护理方法基础上予以系统性护理干预，可缓解晚期NSCLC化疗患者疲乏程度，提高患者的生活质量。

Effect of systematic nursing intervention on cancer-related fatigue in advanced non-small cell lung ;cancer patients undergoing chemotherapy

Objective To explore the effect of systematic nursing intervention on cancer-related fatigue （ CRF） in advanced non-small cell lung cancer （ NSCLC） patients undergoing chemotherapy .Methods Eighty advanced NSCLC patients undergoing chemotherapy were divided into the intervention group and the control group according to the random number table , each with 40 cases.The control group received the routine nursing according to the doctor ’ s advice for tumor patients , and the intervention group received the systematic CRF nursing intervention on the basis of the control group .The CRF and life quality of patients were evaluated by the Brief Fatigue Inventory （ BFI） and the Functional Assessment of Cancer Treatment-Lung （ V3.0） （ FACT-L） before and 15 d after the intervention between the two groups .Results Eighty questionnaires were issued and 80 questionnaires were responsive with an effective response rate of 100%.No difference was found in the degree of fatigue before the intervention between the two groups （P＆gt;0.05）.The degree of CRF in the intervention group was significantly lower than that in the control group after the intervention , and the difference was statistically significant （χ2 =8.47, P=0.04）.The scores of physiological status , social/family status, relationships with physicians , emotional state , functional status , additional attention and total score of scale were respectively （32.15 ＆#177;6.08）, （35.31 ＆#177;5.33）, （12.38 ＆#177;2.67）, （28.59 ＆#177;4.53）, （34.34 ＆#177;5.86）, （43.80 ＆#177;7.76）, （186.57 ＆#177;32.23）in the intervention group, and were （25.45 ＆#177;5.42）, （28.68 ＆#177;4.16）, （9.95 ＆#177;1.49）, （21.87 ＆#177;3.95）, （26.21 ＆#177;5.01）, （36.63 ＆#177;8.24）, （148.79 ＆#177;28.27） in the control group, and the differences were statistically significant （t=5.20, 6.20, 5.03, 7.07, 6.67, 4.01, 5.57, respectively; P＆lt;0.01）.Conclusions The systematic nursing intervention based on routine nursing can alleviate the degree of CRF in advanced NSCLC patients with chemotherapy , and improve the life qualify of patients .