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叶黄素治疗年龄相关性黄斑变性的临床研究
引用本文:夏立营,刘维佳,寇秋爱,周佩云,李跃虹,李明喜,崔坤敏,葛文津.叶黄素治疗年龄相关性黄斑变性的临床研究[J].世界中医药,2013,8(5):517-519.
作者姓名:夏立营  刘维佳  寇秋爱  周佩云  李跃虹  李明喜  崔坤敏  葛文津
作者单位:夏立营 (中国中医科学院西苑医院中医药保健研究中心,北京,100091); 刘维佳 (中国中医科学院西苑医院中医药保健研究中心,北京,100091); 寇秋爱 (中国中医科学院西苑医院中医药保健研究中心,北京,100091); 周佩云 (中国中医科学院西苑医院中医药保健研究中心,北京,100091); 李跃虹 (中国中医科学院西苑医院眼科,北京,100091); 李明喜 (中国中医科学院西苑医院中医药保健研究中心,北京,100091); 崔坤敏 (中国中医科学院西苑医院中医药保健研究中心,北京,100091); 葛文津 (中国中医科学院西苑医院中医药保健研究中心,北京,100091);
摘    要:目的:观察叶黄素治疗年龄相关性黄斑变性的临床疗效。方法:采用随机、对照、双盲方法,观察83例患者服食叶黄素咀嚼片前后137只眼睛视力、眼底黄斑变化。结果:治疗组显效11眼,有效31眼,无效32眼,总有效率56.76%;对照组显效0眼,有效19眼,无效44眼,总有效率30.16%。2组比较有统计学意义(P<0.001)。结论:叶黄素对年龄相关性黄斑变性患者眼底表现及视力有一定改善作用。

关 键 词:临床研究  年龄相关性黄斑变性  叶黄素
收稿时间:2013/1/9 0:00:00

Clinical Trial of Lutein on Treatment of Age-related Macular Degeneration
Xia Liying,Liu Weiji,Kou Qiuai,Zhou Peiyun,Li Yuehong,Li Mingxi,Cui Kunmin,Ge Wenjin.Clinical Trial of Lutein on Treatment of Age-related Macular Degeneration[J].World Chinese Medicine,2013,8(5):517-519.
Authors:Xia Liying  Liu Weiji  Kou Qiuai  Zhou Peiyun  Li Yuehong  Li Mingxi  Cui Kunmin  Ge Wenjin
Institution:1 Chinese Medical Health Care and Research Center; 2 Department of Ophthalmology, Xiyuan Hospital, China Academy of Chinese Medical Sciences ,BeOing 100091, China)
Abstract:Objective: To evaluate the clinical therapeutic effect of Lutein on the treatment of age-related macular degeneration (AMD). Methods: 137 eyes of 83 AMD patients were randomized in a controlled, double blind trial. The treatment group was treated with lutein chewable tablets and the control group were treated with placebo. After 3-month treatment, the changes of distant vision and puncta luteum in OCT were observed. Results:The total effective rate of the treatment group was 56.76%, significant better than 30.16% of the control group (P 〈 0. 001 ). Conclusion: Lutein showed therapeutic effect for age-related macular degeneration, such as improving visual activity, elimination of retina edema and atrophying.
Keywords:Clinical trial  Age-related macular degeneration(AMD)  Lutein
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