| 脑源性神经营养因子在生殖细胞发育过程中的作用 |
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| 引用本文： | 张玲,熊承良. 脑源性神经营养因子在生殖细胞发育过程中的作用[J]. 生殖医学杂志, 2010, 19(1): 79-84. DOI: 10.3969/j.issn.1004-3845.2010.01.020 |
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| 作者姓名： | 张玲 熊承良 |
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| 作者单位： | 华中科技大学同济医学院计划生育研究所,湖北武汉,430030 |
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| 摘 要： | 脑源性神经营养因子（BDNF）是神经营养因子家族成员,不仅在神经系统广泛表达,也在非神经组织如心血管系统、免疫系统、内分泌和生殖系统表达。本文综述了BDNF在生殖细胞发育过程中的表达和作用的研究进展,重点讨论了BDNF在卵泡发育和成熟过程中的表达和可能作用。
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| 关 键 词： | 脑源性神经营养因子 生殖细胞发育 女性生殖系统 BDNF 神经系统 发育过程 发育成熟 心血管 |
The effect of brain-derived neurotrophic factor on germ cell development |
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| ZHANG Ling,XIONG Cheng-liang. The effect of brain-derived neurotrophic factor on germ cell development[J]. Journal of Reproductive Medicine, 2010, 19(1): 79-84. DOI: 10.3969/j.issn.1004-3845.2010.01.020 |
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| Authors: | ZHANG Ling XIONG Cheng-liang |
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| Affiliation: | (Family Planning Research Institute, Tongji Medical College, Huazhong University of Science Technology, Hubei Wuhan 430030) |
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| Abstract: | Brain-derived neurotrophic factor（BDNF）, a member of neurotrophin family, is widely expressed not only in nervous system, but also in the cardiovascular, immune, endocrine and reproductive systems. In this review, the expression and role of BDNF during germ cell development, especially in the process of follicle development and maturation in female reproductive system are discussed. |
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| Keywords: | Brain-derived neurotrophic factor Oocytes Follicle Development |
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