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视觉假体神经刺激器的发展现状和挑战
引用本文:黄伟昌,王国鹤,吴开杰,任秋实.视觉假体神经刺激器的发展现状和挑战[J].中国医学物理学杂志,2010,27(4):2051-2055.
作者姓名:黄伟昌  王国鹤  吴开杰  任秋实
作者单位:1. 上海交通大学生命科学技术学院激光与光子生物医学研究所,上海,200240
2. 北京大学工学院,北京,100000
基金项目:国家重点基础研究发展计划(973计划),国家863计划资助项目,国家自然基金青年科学基金 
摘    要:老年黄斑变性(AMD)和视网膜色素变性(RP)是不可治愈性视网膜疾病致盲的主要原因。针对这两种致盲疾病,研发视觉假体使盲人重见光明已经成为当前科学领域的研究热点之一。而视觉假体刺激器作为视觉假体的关键模块,对传导人工视觉编码信息、获取有效的视觉诱发具有重要的作用。本文首先介绍了多个国际知名视觉假体神经刺激器的设计方案,分析了它们的优缺点。在此基础上,我们着重论述了视觉假体神经刺激器所面临的挑战及未来的发展趋势,包括视觉假体神经刺激器的灵活性设计、低功耗设计和无线数据和能量传输设计。

关 键 词:视觉假体  神经刺激器  无线传输  脑机接口  视觉功能修复

The Development and Challenges of Neural Stimulator for Visual Proshesis
HUANG Wei-chang,WANG Guo-he,WU Kai-jie,REN Qiu-shi.The Development and Challenges of Neural Stimulator for Visual Proshesis[J].Chinese Journal of Medical Physics,2010,27(4):2051-2055.
Authors:HUANG Wei-chang  WANG Guo-he  WU Kai-jie  REN Qiu-shi
Institution:1. Institute of Laser Medicine and Bio-photonies, Shanghai Jiaotong University, Shanghai 200240, China; 2. College of Engineering, Peking University, Beijing 100000, China)
Abstract:Age-related macular degeneration (AMD) and retinitis pigmentosa (RP) are the main reasons resulting in uncurable retinal diseases of blind. Focusing on these two blinding diseases, development of visual prosthesis to enable blind people to see has become a hot topic of scientific research. The visual prosthesis stimulator, as the key module of a visual prosthesis, translates artificial visual coded information and access to effective visual evoked. This article first introduces a number of internationally renowned visual neural stimulator design, analyses their advantages and disadvantages. On this basis, we also focuses on the vi- sual nerve stimulator challenges and future development trends, including the flexibility of the visual nerve stimulator design, lowpower supply desiign, wireless energy and data transmission design.
Keywords:visual prosthesis  neural stimulator  wireless transmission  brain-computer interface  visual functional recovery
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