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大剂量甲基强的松龙冲击治疗小儿急性肺损伤
引用本文:严纯雪,何时军,潘国权,单小鸥,南向珍.大剂量甲基强的松龙冲击治疗小儿急性肺损伤[J].中国小儿急救医学,2002,9(1):22-23.
作者姓名:严纯雪  何时军  潘国权  单小鸥  南向珍
作者单位:温州医学院附属育英儿童医院,浙江,温州,325003
摘    要:目的  采用大剂量甲基强的松龙冲击治疗小儿急性肺损伤 (ALI) ,评价其疗效。 方法  选择 1999年 1月— 2 0 0 1年 6月入住本院儿童ICU急性肺损伤 48例 ,随机分为两组即大剂量甲基强的松龙治疗组和常规治疗组 ,连续监测血氧饱和度、血气分析、FiO2 、X线胸片、呼吸机撤机时间及死亡率。 结果  大剂量甲基强的松龙治疗组PaO2 /FiO2 恢复及胸部X片阴影消退 ,呼吸机撤离及住院时间均明显缩短 ,发展为ARDS及死亡率明显下降。 结论  大剂量甲基强的松龙冲击治疗小儿ALI安全有效

关 键 词:甲基强的松龙  小儿急性肺损伤
文章编号:1007-9459(2002)-01-0022-02
修稿时间:2001年8月15日

A clinical observation on large dose methylprednisolone impact therapy for pedo-acute lung injury
YAN Chun xue,HE Shi jun,PAN Guo quan,et al.A clinical observation on large dose methylprednisolone impact therapy for pedo-acute lung injury[J].Chinese Pediatric Emergency Medicine,2002,9(1):22-23.
Authors:YAN Chun xue  HE Shi jun  PAN Guo quan  
Abstract:Objective There are different opinions on large dose methylprednisolone impact therapy for acute lung injury.To evaluate its effect on pedo acute lung injury,patient were treated with large dose methylprednisolone impact therapy.Methods From Jan,1999 to June,2001 48 cases with acute lung injury were randomly divided into two groups:large dose methylprednilsolone impact therapy group and the control group.Monitoring successively blood oxygen saturation and FiO\-2,blood gas analysis,chest X ray,time of respirator use and the mortality rate.Results All indices observed on large dose methylprednisolone impact therapy group were superior to that of the control group.Conclusion The large dose methylprednisolone impact therapy is safe and effective for pedo ALI.
Keywords:methylprednisolone  pedo  acute lung injury
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