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The significance of elevated CSF lactate
Authors:Chow S L  Rooney Z J  Cleary M A  Clayton P T  Leonard J V
Institution:Metabolic Unit, Great Ormond Street Hospital for Children, London, UK.
Abstract:The final diagnosis of 158 patients who had a cerebrospinal fluid (CSF) lactate concentration greater than 2 mmol/l was ascertained. The conditions included seizures, inflammatory changes, and proven metabolic disorders. For the diagnosis of congenital lactic acidoses, CSF lactate should ideally be measured in a seizure free patient after any acute illness.
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