阻塞性睡眠呼吸暂停低通气综合征并发充血性心力衰竭的机制研究进展

睡眠呼吸暂停低通气综合征是一组常见的睡眠疾病,包括阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)、中枢性睡眠呼吸暂停低通气综合征(central sleep apnea-hypopnea syndrome,CSAHS)和混合性睡眠呼吸暂停低通气综合征(mixed sleep apnea-hypopnea syndrome,MSAHS),其中OSAHS是这组疾病中最常见的一种。近来研究表明随着OSAHS病情逐渐加重,可并发多种心血管疾病,其中充血性心力衰竭是重要合并症之一,研究表明合并心衰会对OSAHS疾病进展及预后产生不利影响,但目前对其机制尚不十分明确,本文就目前国内外OSAHS伴发心衰可能机制进行综述。

Advances in mechanisms of obstructive sleep apnea hypopnea syndrome complicated with congestive heart failure

Sleep apnea hypopnea syndrome is a common group of sleep disorders,including obstructive sleep apneahypopnea syndrome(OSAHS),central sleep apnea-hypopnea syndrome(CSAHS)and mixed sleep apnea-hypopnea syndrome(MSAHS),of which OSAHS is the most common of this group of diseases.Recent studies have shown that with the gradual increase of OSAHS condition,a variety of cardiovascular diseases can be complicated,including congestive heart failure,which is one of the important complications.Studies have showed that combined heart failure will have adverse effect on OSAHS disease progression and prognosis.But its mechanism is still not very clear.This article summarizes the possible mechanisms of OSAHS associated with heart failure at home and abroad.