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急性进展性脑梗死生物学标记物的研究进展
基金项目:黑龙江省卫生计生委科研课题(2017-351);黑龙江省大学生创新创业训练计划项目(201710229037)
摘    要:脑血管病的发病率逐年增加,截至2015年跃升为人类死因的第二位,造成的社会问题越来越大。而在脑血管病中约70%为缺血性,即急性脑梗死。在临床工作中我们发现诊断明确的急性脑梗死患者,在予相关治疗后,仍有20%~40%发生进展加重,即为急性进展性脑梗死,其致死、致残率高。本文针对近几年进展性脑梗死生物学标记物研究现状做一概述,希望能为临床中早期预防脑梗死进展加重提供参考。

关 键 词:急性脑梗死  预警因子  生物学标记物  研究进展  溶血磷脂酸

Research progress on biological markers of acute progressive cerebral infarction
Abstract:The incidence of cerebrovascular diseases increased year by year,and cerebrovascular diseases have jumped to the second cause of human death by 2015,resulting in more and more social problems.And about 70%of cerebrovascular diseases are ischemic,that is,acute cerebral infarction.In clinical work,we found that in patients with clear diagnosis of acute cerebral infarction,20%to 40%occurred aggravated progress after the relevant treatment,that is,acute progressive cerebral infarction,with high death rate and morbidity rate.In this paper,the research status of biological markers of progressive cerebral infarction in recent years was reviewed,hoping to provide a reference for the early prevention of cerebral infarction progress.
Keywords:Acute cerebral infarction  Warning factor  Biological markers  Research progress  Lysophosphatidic acid
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