Assessment of parathyroid glands in hemodialysis patients by using color Doppler sonography |
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Authors: | Umit Aksoy Ozcan Ilay Oktay |
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Institution: | (1) Department of Radiology, Acibadem University School of Medicine, Acibadem Kozyatagi Hastanesi Inonu cd. Okur sk. Kozyatagi, Istanbul, Turkey;(2) Rentip Hemodialysis Center, Bursa, Turkey |
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Abstract: | The aim of this study was to assess the role of color and spectral Doppler ultrasound (CDU) in the evaluation of enlarged
parathyroid glands in hemodialysis patients with secondary hyperparathyroidism. Fourteen hemodialysis patients with elevated
intact parathyroid hormone (iPTH) levels were evaluated prospectively with CDU. The volume of each observed parathyroid gland
and the spectral CDU data (velocities, resistance and pulsatility indices, systolic to diastolic ratio, and flow volume output
(FVO)) were noted. The biochemical data (iPTH, calcium, phosphate levels), and CDU results were analyzed with the Spearman
correlation test. Two patients were excluded, and 27 enlarged parathyroid glands were observed in 12 patients. The mean total
volume of enlarged parathyroid glands per patient was 1.95 cm3 (0.06–5.5 cm3). Arterial supply was demonstrated in 78% (21/27) of enlarged parathyroid glands. Mean total FVO of enlarged glands per patient
was 238.5 ml/min (620–0 ml/min) and mean iPTH level was 1,477 pg/ml (643–3,132 pg/ml). The positive correlations of total
volume (p = 0.022), iPTH (p = 0.024), and FVO (p = 0.022) were statistically significant. In secondary hyperparathyroidism, total volume of the visualized enlarged parathyroid
glands and the total of FVOs per patient are positively correlated with iPTH levels which may help clinical management and
follow-up of end-stage renal disease patients. |
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