| 麻醉药及其辅助药物基因组学的研究进展 |
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| 引用本文： | 邓婕,侯颖,宋洪涛. 麻醉药及其辅助药物基因组学的研究进展[J]. 药学服务与研究, 2009, 9(6): 417-421 |
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| 作者姓名： | 邓婕 侯颖 宋洪涛 |
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| 作者单位： | 1. 南京军区福州总医院药学科,福州,350025;沈阳药科大学药学院药剂学教研室,沈阳,110016
2. 南京军区福州总医院药学科,福州,350025 |
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| 摘 要： | 临床上麻醉药及其辅助药物治疗的个体化差异备受关注。目前，越来越多的研究着重于麻醉药物与转运蛋白、作用靶受体和代谢酶的基因多态性之间的关系．并发现麻醉药物效应与相关基因多态性存在密切联系。本文就近年来麻醉药及其辅助药物基因组学的研究进展作一综述。
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| 关 键 词： | 麻醉药 药物基因组学 多态现象 遗传 综述 |
Advances in research on pharmacogenomics of anesthetics and their adjuvants |
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| DENG Jie,HOU Ying,SONG Hong-tao. Advances in research on pharmacogenomics of anesthetics and their adjuvants[J]. Pharmaceutical Care and Research, 2009, 9(6): 417-421 |
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| Authors: | DENG Jie HOU Ying SONG Hong-tao |
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| Affiliation: | 1. Department of Pharmacy. Fuzhou General Hospital of Nanjing Military Region,Fuzhou 350025, China; 2. Department of Pharmaceuties, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China) |
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| Abstract: | The individual difference of anesthetics and their adjuvants in the clinical treatment has received special concern. Currently, more and more researches focus on the relationship between anesthetics and the genetic polymorphisms of transport proteins, targeted receptors and metabolic enzymes. Meanwhile, it has been found that the action of anesthetics has close connection with related genetic polymorphisms. This article presents an overview of the current research progress of pharmacogenomics of anesthetics and their adjuvants. |
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| Keywords: | anesthetics pharmacogenomics polymorphism genetic review |
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