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预防艾滋病和其他性传播疾病的杀微生物剂研究进展
引用本文:张冬梅,曾忠铭,兰建萍. 预防艾滋病和其他性传播疾病的杀微生物剂研究进展[J]. 中国新药与临床杂志, 2006, 25(8): 629-632
作者姓名:张冬梅  曾忠铭  兰建萍
作者单位:1. 广东药学院,广东,广州,510006
2. 深圳市南山区人民医院,广东,深圳,518052
3. 暨南大学第一附属医院,广东,广州,510632
摘    要:从竞争情报的视角介绍了全球29个用于预防艾滋病和其他性传播疾病的阴道局部用候选杀微生物剂的名称、作用机制、剂型、有无避孕作用分类、发明专利申请和获得情况、新药开发所处阶段和研发机构。分析了阴道局部用杀微生物剂在技术开发和市场推广方面面临的困难和挑战。

关 键 词:性传播疾病  获得性免疫缺陷综合征  预防和防护用药  杀微生物剂
文章编号:1007-7669(2006)08-0629-04
收稿时间:2005-11-09
修稿时间:2005-11-092006-07-20

Progress on microbicides to prevent acquired immunodeficiency syndrome and sexually transmitted diseases
ZHANG Dong-mei,ZENG Zhong-ming,LAN Jian-ping. Progress on microbicides to prevent acquired immunodeficiency syndrome and sexually transmitted diseases[J]. Chinese Journal of New Drugs and Clinical Remedies, 2006, 25(8): 629-632
Authors:ZHANG Dong-mei  ZENG Zhong-ming  LAN Jian-ping
Affiliation:1.Guangdong Pharmaceutical University, Guangzhou GUANGDONG 510006, China; 2.Shenzhen Nanshan Hospital, Shenzhen GUANGDONG 518052, China; 3.The First Affiliated Hospital of Ji-nan University, Guangzhou GUA NGDONG 510632, China
Abstract:Twenty-nine global topical microbicide candidates for preventing acquired immunodeficiency syndrome(AIDS)and sexually transmitted diseases(STDS)are introduced in thisarticle from competitive in- telligence perspective.The names,mechanism of actions,formulations,indications for HIV/STDS and contra- ceptive,patent's application and possession,phase of clinical trials,and developers of these microbicide can- didates are introduced.Difficulties and challenges in technology development and market introduction for safe and effective microbicides are analyzed.
Keywords:sexually transmitted diseases   acquired immunodeficiency syndrome   protective agents  microbicides
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