缺氧缺血性脑病新生患儿脐血神经元特异性烯醇化酶分析

目的：分析缺氧缺血性脑病（HIE）新生患儿脐血神经元特异性烯醇化酶（NSE）水平,为防治婴幼儿脑瘫提供依据.方法：缺氧缺血性脑病新生患儿26例为观察组,同期出生的26例正常足月新生儿为对照组.收集脐血检测神经元特异性烯醇化酶.结果：对照组血清神经元特异性烯醇化酶水平均值为（8.3±2.6）μg/L,而观察组为（38.5±18.7）μg/L,明显高于对照组,差异有统计学意义（P＜0.05）.结论：新生患儿脐血神经元特异性烯醇化酶是缺氧缺血性脑病重要指标.

Analysis of cord blood neuron specific enolase in neonates with hypoxic ischemic encephalopathy

Objective： To analyze cord blood neuron specific enolase （NSE） of neonates with hypoxic ischemic encephalopathy （HIE）, and to provide an important basis for preventing infantile cerebral palsy. Methods： Randomly selected 26 neonates with HIE for the observation and 26 full-term newborns as control. The neonatal umbilical cord blood was collected for the determination of NSE levels. Results： The average serum NSE level was （8. 3±2.6）/lg/L in observation group that was significantly higher than （38.5±18.7）μg/L in control group （P〈0.05）. Conclusion： NSE in neonatal cord blood can serve as predictor of neonatal hypoxic ischemic encephalopathy.