发病6-8h急性脑梗死用尿激酶溶栓治疗的临床分析

目的探讨观察发病6～8h急性脑梗死患者使用尿激酶进行溶栓治疗的疗效及安全性。方法选择发病6-8h的急性脑梗死患者17例，予尿激酶150万U加入100mL的生理盐水，取15mL静脉推注后，余85mL在60min内静脉滴注溶栓。溶栓后予降颅内压，抗凝，抗血小板营养剂等综合治疗。结果使用尿激酶溶栓治疗后，总有效率为70．59％，NDS值（12．6±3．7）和BI值（3．24±0．86）都较溶栓前小。结论发病6～8h急性脑梗死用尿激酶溶栓治疗安全有效。

Clinical Analysis of Thrombolysis by Urokinase for Acute Cerebral Infrac- tion Attacking Within 6-8 Hours

Objective To observe the effect and safety of urokinase thrombolytic therapy for treating acute cerebral infarction at- tacking within 6-8 hours. Methods 17 patients attacked by acute cerebral infarction within 6-8 hours were chosen. Dissolving 1.5 million unit urokinases in 100ml normal saline, then intravenously injecting 15ml of the mixed solution and intravenously dripping the rest 85 ml in 60 minutes to these patients. In addition, the patients were treated with reducing intracranial pressure, anticoagu- lation, blood glucose and blood pressure control therapies. Results The total effective rate of the patients after thrombolytic therapy was 70.59%. And the score of NDS（12.6±3.7） and BI （3.24±0.86）were significantly lower than those before the treatment. Con- clusion The urokinase thrombolytic therapy is effective and safe for treating the acute cerebral infarction attacking within 6-8 hours.