胃肠间质瘤的临床诊断与外科治疗分析简

目的探讨胃肠间质瘤（GIST）的诊断和治疗。方法回顾性分析2004年8月至2013年9月收治的经手术治疗的244例GIST病人的临床资料。结朵24例病人均行手术，术后病理确诊为GIST。其中胃18例，小肠6例。24例完整手术切除。所有病例均随访，4例于术后1-3年发现肿瘤复发伴肝脏、腹腔转移，无法手术死亡。结论GIST起病隐匿，早期确诊相对困难，首选治疗方法是根治性切除，术后辅助应用甲磺酸伊马替尼可减少复发和改善预后。

Analysis of Clinical Diagnosis and Surgical Treatment of Gastrointestinal Stromal Tumor

Objective To explore the method for diagnosis and treatment of gastrointestinal stromal tumor （GIST）. Mothods The clinical data of 24 cases of GIST treated by surgical operation in this hospital from August 2004 to September 2013 were retrospectively analyzed. Results These 24 patients had been operated and GIST had been proved by pathological examination. In this series of patients, the tumor had been found in stomach （n=18） , small intestine （n=6） . GIST in 24 cases had completely been resected .All of the case were followed up.In 4 cases of 1-3 years of tumor recurrence was found with the liver, peritoneal metastasis, no operation death. Conclusion GIST insidious onset, early diagnosis is difficult.The first choice for treatment of GIST is curative resection, and adjuvant therapy with imatinib mesylate can reduce the recurrence of tumor, thus it may improve the prognosis and raise the survival rate of patients.