Dukes C期结直肠癌根治术后复发转移因素的Logistic回归分析

目的:探讨Dukes C期结直肠癌根治术后复发转移的相关因素。方法:应用Logistic回归分析方法，对235例结直肠癌根治术后患者的临床病理资料，进行单因素和多因素回顾分析。结果：单因素分析显示，患者性别、年龄、病程、肿瘤部位、肿瘤大体类型、肿瘤直径、肿瘤组织类型及肠壁浸润深度对结直肠癌术后复发转移无影响。单因素和多因素分析显示，淋巴结转移和肿瘤分化程度是影响结直肠癌术后复发转移的独立预后因素。结论：淋巴结转移(数目或部位)和肿瘤分化程度是影响Dukes C期结直肠癌术后复发转移最重要的独立因素，对于判断预后、指导术后治疗及随访方案的制订具有重要作用。

Logistic Regression Analysis of Recurrence and Metastasis Following Radical Operation in Colorectal Cancer at Dukes C Stage

Objective To investigate the clinicopathologic factors related with recurrence and metastasis following radical operation in colorectal cancer at Dukes C stage.Methods The clinicopathologic factors and follow-up data of 235 cases of colorectal cancers after surgical treatment were analyzed using logistic regression models.Results Single and multiple factors analysis showed that lymph node metastasis and histological differentiation significantly associated with recurrence and metastasis.But age,gender,course of disease,tumor location,gross findings,histological type,tumor size and depth of bowel wall invasion were not related with recurrence and metastasis.Conclusion Lymph node metastases(number or site) and histological differentiation were the most important independent factors for recurrence and metastasis.They may be useful for prognosis and making the postoperative treatment and follow-up program for patients at Dukes C stage.