| 非致死剂量超声对卵巢癌细胞超微结构的影响 |
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| 引用本文： | 于廷和,王国云,蔡汉钟,王智彪.非致死剂量超声对卵巢癌细胞超微结构的影响[J].中国超声医学杂志,1999,15(9):647-648. |
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| 作者姓名： | 于廷和 王国云 蔡汉钟 王智彪 |
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| 作者单位： | 1. 250012,济南市山东医科大学附属医院
2. 重庆市重庆医科大学医学超声工程研究所 |
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| 基金项目： | 九五国家重点攻关项目资助 |
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| 摘 要： | 目的⑶研究非致死剂量超声对体外培养的人卵巢癌细胞超微结构的影响⒚方法⑶卵巢癌细胞 ３ Ａ Ｏ 受非致死剂量超声辐照后⒙观察其超微结构的变化⒚结果⑶大部分受辐照细胞形态学变化不明显⒚部分细胞线粒体肿胀、嵴断裂、甚至膜破裂⒙胞浆内出现空泡⒚结论⑶非致死剂量超声可能通过空化效应而致卵巢癌细胞线粒体损伤⒚
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| 关 键 词： | 卵巢癌 细胞 超声 空化 |
Effects of Ultrasound of Nonlethal Dosage on Ultrastructure of Human Ovarian Carcinoma Cell Line 3AO in vitro |
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| Yu Tinghe,Wang Guoyun,Cai Hanzhong,et al Affiliated Hospital of Shandong Medical University Jinan.Effects of Ultrasound of Nonlethal Dosage on Ultrastructure of Human Ovarian Carcinoma Cell Line 3AO in vitro[J].Chinese Journal of Ultrasound in Medicine,1999,15(9):647-648. |
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| Authors: | Yu Tinghe Wang Guoyun Cai Hanzhong Affiliated Hospital of Shandong Medical University Jinan |
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| Institution: | Yu Tinghe,Wang Guoyun,Cai Hanzhong,et al Affiliated Hospital of Shandong Medical University Jinan 250012 |
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| Abstract: | Objective:To determine the effects of nonlethal dosage ultrasound on ultrastructure of human ovarian carcinoma cell line 3AO in vitro.Methods:3AO cells were exposed to nonlethal ultrasound.Their ultrastructure alterations were inspected and compared with cells sham irradiated.Results:No significant ultrastructure alterations in most cells were observed,although swollen mitochondria,fractured ridge,even ruptured membrane and cytoplasmic cavitations appeared in some irradiated cells.Conclusion:Nonlethal dosage ultrasound could lead mitochondria damage to ovarian carcinoma by cells cavitation. |
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| Keywords: | Ovarian carcinoma Cell line Ultrasound Cell cavitation |
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