| 中枢神经系统突触发生研究方法概述 |
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| 引用本文： | 李常新,黄如训.中枢神经系统突触发生研究方法概述[J].中国组织工程研究与临床康复,2003,7(5):778-779. |
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| 作者姓名： | 李常新 黄如训 |
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| 作者单位： | 中山大学附属第一医院神经科,广东省,广州市,510080 |
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| 摘 要： | 突触是神经元进行信息交换的特殊部位。突触发生中神经元突起通过延伸、辨认相应的靶细胞并与其接触形成稳定的突触。晚近的一些实验方法对突触发生做了研究,认为电镜、电生理、免疫组织化学及实时荧光成像等多种方法相结合进行研究更可信。研究突触发生可能有助于进一步探讨中枢神经系统疾病的康复机制。
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| 关 键 词： | 突触/生理学 突触/免疫学 神经无可塑性 康复 |
| 文章编号： | 1671-5926(2003)05-0778-02 |
| 修稿时间： | 2002年11月20 |
Overview for experimental techniques about synaptogenesis in central nervous system |
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| Li Changxin,Huang RuxunLi Changxin,Huang Ruxun.Overview for experimental techniques about synaptogenesis in central nervous system[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2003,7(5):778-779. |
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| Authors: | Li Changxin Huang RuxunLi Changxin Huang Ruxun |
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| Institution: | Li Changxin,Huang RuxunLi Changxin,Huang Ruxun,Department of Neurology,First Affiliated Hospital,Sun Yat sen University of Medical Sciences,Guangzhou 510080,China |
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| Abstract: | Synapses of the central nervous system(CNS) are specialized sites of cell cell contact designed for the signaling between neurons and their targets. Synaptogenesis involves extension of neural dendrites, identification of target cells and forming stable synapse. Until recently, new experimental techniques are beginning to illuminate the processes involved in synaptogenesis.Combing multiple methods such as electron micrograph,electrophysiology,immunohistochemistry and real time fluorescence imaging,in the study of CNS synaptogenesis seems unavoidable at present.The study of synaptogenesis may be helpful for understanding the rehabilitation mechanism of CNS diseases. |
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| Keywords: | synapses/physiology synapses/immundogy neuronal plasticity rehabilitation |
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