| 南京地区孕妇弓形虫感染不同妊娠结局研究 |
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| 引用本文： | 夏薇,张小俊,陈锡慰.南京地区孕妇弓形虫感染不同妊娠结局研究[J].中国血吸虫病防治杂志,2011,23(2):183-186. |
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| 作者姓名： | 夏薇 张小俊 陈锡慰 |
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| 作者单位： | 1. 江苏省南京市疾病预防控制中心 南京210003
2. 南京医科大学病原生物学系 |
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| 摘 要： | 目的探讨孕妇怀孕不同时期弓形虫感染对妊娠结局的影响。方法采用问卷调查、随访和酶联免疫吸附试验（ELISA）检测南京地区6 849名孕妇外周血弓形虫IgG抗体和IgM抗体以及1 032名新生儿脐血弓形虫IgM抗体,并观察孕妇妊娠结局。结果共筛查孕妇6 849例,抗体阳性438例,阳性率为6.4%。其中弓形虫lgM抗体阳性87例,占19.9%;IgG抗体阳性351例,占80.1%。筛查新生儿1 032名,其中正常新生儿组脐血弓形虫IgM抗体阳性率为0.6%,畸形儿组脐血弓形虫IgM抗体阳性率为28.13%,两组差异有统计学意义（P〈0.01）。接触动物及不良的饮食习惯（经常在外就餐、喜欢吃烧烤和火锅、喜欢生食肉类、菜板生熟不分等）是导致弓形虫感染的主要传播途径。结论弓形虫感染可导致孕妇不同的妊娠结局,弓形虫lgM抗体检测可能有助于筛选畸形儿。
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| 关 键 词： | 弓形虫感染 妊娠结局 IgM抗体 IgG抗体 孕妇 新生儿 |
Investigation of different pregnant results of pregnant women infected with Toxoplasma gondii in Nanjing region |
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| Xia Wei,Zhang Xiao-jun,Chen Xi-wei.Investigation of different pregnant results of pregnant women infected with Toxoplasma gondii in Nanjing region[J].Chinese Journal of Schistosomiasis Control,2011,23(2):183-186. |
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| Authors: | Xia Wei Zhang Xiao-jun Chen Xi-wei |
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| Institution: | Xia Wei1,Zhang Xiao-jun1,Chen Xi-wei21 Nanjing Municipal Center for Disease Control and Prevention,Nanjing 210003,China,2 Department of Pathogenic Biology,Nanjing Medical University |
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| Abstract: | Objective To explore the influence of Toxoplasma gondii infection on pregnant results during different pregnancies of women.Methods The antibodies of IgG and IgM against Toxoplasma gondii in peripheral blood were detected by ELISA in 6 849 pregnant women and the antibody of IgM against Toxoplasma gondii in cord blood was also detected in 1 032 newborns in Nanjing City.The general status of these women was investigated with questionnaire,and the outcome of pregnancies of the women was followed up.Results A t... |
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| Keywords: | Toxoplasma gondii infection Pregnant result Antibody IgM Antibody IgG Pregnant women Newborn |
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