In Vitro Activity of a New Polyene, SPA-S-843, against Yeasts |
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| Authors: | C Rimaroli and T Bruzzese |
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| Institution: | Research Laboratories, Società Prodotti Antibiotici SpA, 20143 Milan, Italy |
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| Abstract: | The in vitro activity of a new water-soluble polyene, SPA-S-843, was evaluated against 116 strains of Candida, Cryptococcus, and Saccharomyces spp. and compared with that of amphotericin B. SPA-S-843 demonstrated better inhibitory activity against all of the yeasts examined and better fungicidal activity against Candida albicans, Candida glabrata, Candida krusei, and Candida tropicalis than did amphotericin B. |
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