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Portable negative‐pressure wound therapy for pyoderma gangrenosum: Report of two cases
Authors:Yasuyuki Yamaguchi  Teruki Yanagi  Kazumasa Sato  Norihiro Yoshimoto  Yu Hirata  Inkin Ujiie  Machiko Nishimura  Ken Natsuga  Chihiro Shiiya  Ichiro Tsukinaga  Hiroshi Shimizu
Institution:1. Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan;2. Department of Dermatology, KKR Sapporo Medical Center, Sapporo, Japan
Abstract:Pyoderma gangrenosum is a chronic non‐infectious neutrophilic dermatosis that causes undermining ulcers. Topical therapies for the deep ulcers of pyoderma gangrenosum have not been established. To investigate whether negative‐pressure wound therapy is effective for a pyoderma gangrenosum ulcer, we used the PICO single use negative‐pressure wound therapy system (Smith & Nephew, London, UK) for two pyoderma gangrenosum patients. In these cases, the ulcers decreased in size and necrolytic tissue was removed notably. Moreover, there were no secondary infections nor was there Koebner phenomena. Our cases suggest that portable negative‐pressure wound therapy can be a treatment option for deep, intractable ulcers caused by pyoderma gangrenosum. Because portable negative‐pressure wound therapy devices afford increased mobility to patients, they can give the patient a better quality of life than standard negative‐pressure wound therapy systems do.
Keywords:negative‐pressure wound therapy  PICO single use negative‐pressure wound therapy system  portable negative‐pressure wound therapy device  pyoderma gangrenosum  ulcer
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