肺灌注显像评价急性肺栓塞药物治疗的疗效

目的 :评价99mTc MAA肺灌注显像对判断急性肺栓塞溶栓继以抗凝治疗的效果及预后价值。方法 :肺栓塞患者 16例 ,治疗前、治疗后 1周、1个月和 3个月均行肺灌注显像 ,结果 :患者经溶栓继以抗凝治疗 1周后 ,临床好转 ,肺灌注显像 42 .2 %的稀疏缺损区得到不同程度的放射性填充 ;1个月及 3个月后复查 ,分别有 6 6 .9%、72 .1%的稀疏缺损区得到不同程度的放射性填充。结论 :肺灌注显像为无创性检查 ,根据稀疏缺损变化可随访观察肺栓塞的消退 ,选择用药并及时调整治疗方案。

Evaluation of Effect of Drug Therapy in Acute Pulmonary Embolism by Pulmonary Perfusion Scintigraphy

Objective:To access the value of 99m Tc MAA pulmonary perfusion imaging in evaluation of thrombolytic effects and prognosis in patients with acute pulmonary embolism (PE).Methods:Sixteen patients with PE underwent 99m Tc MAA pulmonary perfusion imaging before thrombolytic therapy.The repeated scintigraphy was performed at 1 week,1 month and three months after therapy.Results:The clinical symptoms or physical signs improved at 1 week after thrombolytic therapy.At 1 week,1 month and 3 months after thrombolytic therapy, recovered perfusion was shown in 42.2% , 66.9% and 72.1% of the radioactive defect segments,respectively.Conclusions:Pulmonary perfusion imaging is a non invasive diagnostic method.According to the change of radioactivity distribution,the perfusion state of embolitic region may be followed up.Thus,it may be also helpful to take reasonable and optimal treatments for the patients.